Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Metabotropic glutamate receptor 4 [Q124R] (Rattus norvegicus) | BDBM50293721 (CHEMBL562551 | N-(4-chloro-3-methoxyphenyl)picolin...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | n/a | n/a | 107 | n/a | n/a | n/a | n/a |
Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters Curated by PubChem BioAssay | Assay Description Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2DR2SWV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat)) | BDBM50293721 (CHEMBL562551 | N-(4-chloro-3-methoxyphenyl)picolin...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 110 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center Curated by ChEMBL | Assay Description Activity at rat mGluR4 receptor expressed in HEK293 cells assessed as effect on thallium flux | J Med Chem 52: 4115-8 (2009) Article DOI: 10.1021/jm9005065 BindingDB Entry DOI: 10.7270/Q2RJ4JHT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 4 (Homo sapiens (Human)) | BDBM50293721 (CHEMBL562551 | N-(4-chloro-3-methoxyphenyl)picolin...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | n/a | n/a | 239 | n/a | n/a | n/a | n/a |
Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters Curated by PubChem BioAssay | Assay Description Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2VT1QHF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 4 (Homo sapiens (Human)) | BDBM50293721 (CHEMBL562551 | N-(4-chloro-3-methoxyphenyl)picolin...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 240 | n/a | n/a | n/a | n/a |
Lundbeck Research USA, Inc. Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu4 receptor expressed in BHK cells assessed as potentiation of glutamate-induced calcium mobilization afte... | J Med Chem 54: 5070-81 (2011) Article DOI: 10.1021/jm200290z BindingDB Entry DOI: 10.7270/Q26110P5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 4 (Homo sapiens (Human)) | BDBM50293721 (CHEMBL562551 | N-(4-chloro-3-methoxyphenyl)picolin...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 240 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center Curated by ChEMBL | Assay Description Activity at human mGluR4 receptor expressed in CHO cells assessed as effect on calcium mobilization | J Med Chem 52: 4115-8 (2009) Article DOI: 10.1021/jm9005065 BindingDB Entry DOI: 10.7270/Q2RJ4JHT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (RAT) | BDBM50293721 (CHEMBL562551 | N-(4-chloro-3-methoxyphenyl)picolin...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | n/a | n/a | 2.34E+3 | n/a | n/a | n/a | n/a |
Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters Curated by PubChem BioAssay | Assay Description Assigned Assay Grant Number: NS053536-01 Screening Center Name & PI: Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters, C. David W... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2HH6HG6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50293721 (CHEMBL562551 | N-(4-chloro-3-methoxyphenyl)picolin...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | n/a | n/a | 2.42E+3 | n/a | n/a | n/a | n/a |
Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters Curated by PubChem BioAssay | Assay Description Assigned Assay Grant Number: NS053536-01 Screening Center Name & PI: Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters, C. David W... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q25719GZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 8 (Rattus norvegicus (Rat)) | BDBM50293721 (CHEMBL562551 | N-(4-chloro-3-methoxyphenyl)picolin...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | n/a | n/a | 6.17E+3 | n/a | n/a | n/a | n/a |
Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters Curated by PubChem BioAssay | Assay Description Assigned Assay Grant Number: NS053536-01 Screening Center Name & PI: Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters, C. David W... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2T1523G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat)) | BDBM50293721 (CHEMBL562551 | N-(4-chloro-3-methoxyphenyl)picolin...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | n/a | n/a | 4.45E+5 | n/a | n/a | n/a | n/a |
Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters Curated by PubChem BioAssay | Assay Description Assigned Assay Grant Number: NS053536-01 Screening Center Name & PI: Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters, C. David W... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2P849B9 | |||||||||||
More data for this Ligand-Target Pair |