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Compile Data Set for Download or QSAR

Found 1 hit of ec50 for monomerid = 50314999   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Amyloid-beta precursor protein


(Homo sapiens (Human))		BDBM50314999
PNG
(6-((2-(2-chlorophenyl)-5-(4-(pyrazin-2-yloxy)pheny...)
Show SMILES Nc1cccc(Cn2c(ccc2-c2ccccc2Cl)-c2ccc(Oc3cnccn3)cc2)n1
Show InChI InChI=1S/C26H20ClN5O/c27-22-6-2-1-5-21(22)24-13-12-23(32(24)17-19-4-3-7-25(28)31-19)18-8-10-20(11-9-18)33-26-16-29-14-15-30-26/h1-16H,17H2,(H2,28,31)
PDB
MMDB

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Similars
Article
PubMed
n/an/an/an/a 1.33E+4n/an/an/an/a



Princ

Curated by ChEMBL


Assay Description
Inhibition of human recombinant APP in CHO cells assessed as decrease in beta amyloid protein level by ELISA

Bioorg Med Chem Lett 20: 2068-73 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.075
BindingDB Entry DOI: 10.7270/Q2PG1RWS
More data for this
Ligand-Target Pair