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Compile Data Set for Download or QSAR

Found 1 hit of ec50 for monomerid = 50327484   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(Homo sapiens (Human))		BDBM50327484
PNG
(2-(2-hydroxyethyl)-8-(1-isopropylpiperidin-4-yloxy...)
Show SMILES CC(C)N1CCC(CC1)Oc1ccc2n3CCN(CCO)C(=O)c3cc2c1
Show InChI InChI=1S/C21H29N3O3/c1-15(2)22-7-5-17(6-8-22)27-18-3-4-19-16(13-18)14-20-21(26)23(11-12-25)9-10-24(19)20/h3-4,13-15,17,25H,5-12H2,1-2H3
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Article
PubMed
n/an/an/an/a 56n/an/an/an/a



F Hoffmann-La Roche Ltd

Curated by ChEMBL


Assay Description
Inverse agonist activity at human recombinant histamine H3 receptor assessed as effect on [35S]GTPgammaS binding

Bioorg Med Chem Lett 20: 5713-7 (2010)


Article DOI: 10.1016/j.bmcl.2010.08.009
BindingDB Entry DOI: 10.7270/Q2571C7N
More data for this
Ligand-Target Pair