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Compile Data Set for Download or QSAR

Found 1 hit of ec50 for monomerid = 50334127   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Prostaglandin E2 receptor EP4 subtype


(Homo sapiens (Human))
BDBM50334127
PNG
((S)-4-(1-(1-(3-chlorobenzyl)indoline-7-carboxamido...)
Show SMILES C[C@H](NC(=O)c1cccc2CCN(Cc3cccc(Cl)c3)c12)c1ccc(cc1)C(O)=O |r|
Show InChI InChI=1S/C25H23ClN2O3/c1-16(18-8-10-20(11-9-18)25(30)31)27-24(29)22-7-3-5-19-12-13-28(23(19)22)15-17-4-2-6-21(26)14-17/h2-11,14,16H,12-13,15H2,1H3,(H,27,29)(H,30,31)/t16-/m0/s1
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Similars

Article
PubMed
n/an/an/an/a 0.820n/an/an/an/a



Merck Frosst Canada Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human prostanoid EP4 receptor expressed in HEK293 cells assessed as potentiation of PGE2-induced cAMP accumulation by scintillati...


Bioorg Med Chem Lett 21: 484-7 (2010)


Article DOI: 10.1016/j.bmcl.2010.10.106
BindingDB Entry DOI: 10.7270/Q2BZ6695
More data for this
Ligand-Target Pair