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Compile Data Set for Download or QSAR

Found 2 hits of ec50 for monomerid = 50435198   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Methionine aminopeptidase 1


(Homo sapiens (Human))
BDBM50435198
PNG
(CHEMBL2392918)
Show SMILES Cc1nc(nc(NC[C@H](NCc2ccccc2)c2ccccc2)c1Cl)-c1ccc(Cl)cn1 |r|
Show InChI InChI=1S/C25H23Cl2N5/c1-17-23(27)25(32-24(31-17)21-13-12-20(26)15-29-21)30-16-22(19-10-6-3-7-11-19)28-14-18-8-4-2-5-9-18/h2-13,15,22,28H,14,16H2,1H3,(H,30,31,32)/t22-/m0/s1
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PC cid
PC sid
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Similars

Article
PubMed
n/an/an/an/a 220n/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...


Bioorg Med Chem 21: 2600-17 (2013)


Article DOI: 10.1016/j.bmc.2013.02.023
BindingDB Entry DOI: 10.7270/Q290256X
More data for this
Ligand-Target Pair
Microtubule-associated protein 2


(Homo sapiens (Human))
BDBM50435198
PNG
(CHEMBL2392918)
Show SMILES Cc1nc(nc(NC[C@H](NCc2ccccc2)c2ccccc2)c1Cl)-c1ccc(Cl)cn1 |r|
Show InChI InChI=1S/C25H23Cl2N5/c1-17-23(27)25(32-24(31-17)21-13-12-20(26)15-29-21)30-16-22(19-10-6-3-7-11-19)28-14-18-8-4-2-5-9-18/h2-13,15,22,28H,14,16H2,1H3,(H,30,31,32)/t22-/m0/s1
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 3.10E+4n/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of human recombinant GST-6XHis-tagged full-length cytosolic METAP2 expressed in cabbage looper BTI-TN-5B1-4 cells using Met-Pro-p-nitroani...


Bioorg Med Chem 21: 2600-17 (2013)


Article DOI: 10.1016/j.bmc.2013.02.023
BindingDB Entry DOI: 10.7270/Q290256X
More data for this
Ligand-Target Pair