Found 2 hits of ec50 for monomerid = 50439404 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
G protein-activated inward rectifier potassium channel 1
(Homo sapiens (Human)) | BDBM50439404
(CHEMBL2420539)Show SMILES CN(C)S(=O)(=O)c1cc(NC(=O)Cc2ccc(F)cc2)ccc1C Show InChI InChI=1S/C17H19FN2O3S/c1-12-4-9-15(11-16(12)24(22,23)20(2)3)19-17(21)10-13-5-7-14(18)8-6-13/h4-9,11H,10H2,1-3H3,(H,19,21) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 3.60E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description Activation of GIRK1/2 (unknown origin) by cell-based thallium flux assay |
Bioorg Med Chem Lett 23: 5195-8 (2013)
Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1 |
More data for this Ligand-Target Pair | |
G protein-activated inward rectifier potassium channel 4
(Homo sapiens (Human)) | BDBM50439404
(CHEMBL2420539)Show SMILES CN(C)S(=O)(=O)c1cc(NC(=O)Cc2ccc(F)cc2)ccc1C Show InChI InChI=1S/C17H19FN2O3S/c1-12-4-9-15(11-16(12)24(22,23)20(2)3)19-17(21)10-13-5-7-14(18)8-6-13/h4-9,11H,10H2,1-3H3,(H,19,21) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 5.20E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description Activation of GIRK1/4 (unknown origin) by cell-based thallium flux assay |
Bioorg Med Chem Lett 23: 5195-8 (2013)
Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1 |
More data for this Ligand-Target Pair | |