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Compile Data Set for Download or QSAR

Found 2 hits of ec50 for monomerid = 50440488   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50440488
PNG
(CHEMBL2426147)
Show SMILES CC(C)(C(c1ccccc1)c1ccc2c(ncn2c1)-c1ccc(F)cc1F)C(=O)Nc1nncs1
Show InChI InChI=1S/C26H21F2N5OS/c1-26(2,24(34)31-25-32-30-15-35-25)22(16-6-4-3-5-7-16)17-8-11-21-23(29-14-33(21)13-17)19-10-9-18(27)12-20(19)28/h3-15,22H,1-2H3,(H,31,32,34)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 15n/an/an/an/a



Bristol-Myers Squibb Company

Curated by ChEMBL


Assay Description
Transrepression of glucocorticoid receptor in human A549 cells assessed as inhibition of PMA-induced AP-1 activity by luciferase reporter gene assay


Bioorg Med Chem Lett 23: 5571-4 (2013)


Article DOI: 10.1016/j.bmcl.2013.08.049
BindingDB Entry DOI: 10.7270/Q2QC04Z4
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50440488
PNG
(CHEMBL2426147)
Show SMILES CC(C)(C(c1ccccc1)c1ccc2c(ncn2c1)-c1ccc(F)cc1F)C(=O)Nc1nncs1
Show InChI InChI=1S/C26H21F2N5OS/c1-26(2,24(34)31-25-32-30-15-35-25)22(16-6-4-3-5-7-16)17-8-11-21-23(29-14-33(21)13-17)19-10-9-18(27)12-20(19)28/h3-15,22H,1-2H3,(H,31,32,34)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 117n/an/an/an/a



Bristol-Myers Squibb Company

Curated by ChEMBL


Assay Description
Transactivation of GR-LBD expressed in human HeLa cells co-expressing GAL4-DBD by luciferase reporter gene assay


Bioorg Med Chem Lett 23: 5571-4 (2013)


Article DOI: 10.1016/j.bmcl.2013.08.049
BindingDB Entry DOI: 10.7270/Q2QC04Z4
More data for this
Ligand-Target Pair