Compile Data Set for Download or QSAR

Found 6 hits of ec50 for monomerid = 65179   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sphingosine-1-phosphate lyase 1 (Homo sapiens (Human))	BDBM65179 (US10166249, Example 525 | US9522888, 525) Show SMILES N[C@]1(COP(O)(O)=O)CC[C@@H](C1)c1ccc2C[C@H](CSCCc3ccncc3)CCc2c1 |r| Show InChI InChI=1S/C24H33N2O4PS/c25-24(17-30-31(27,28)29)9-5-23(15-24)22-4-3-20-13-19(1-2-21(20)14-22)16-32-12-8-18-6-10-26-11-7-18/h3-4,6-7,10-11,14,19,23H,1-2,5,8-9,12-13,15-17,25H2,(H2,27,28,29)/t19-,23+,24-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	<10	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description hS1P1/CHO cells were plated into BD Amine 384-well plates the day before the assay. On the day of the assay, growth medium was removed and replaced w...				US Patent US10166249 (2019) BindingDB Entry DOI: 10.7270/Q2S75JCM
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM65179 (US10166249, Example 525 | US9522888, 525) Show SMILES N[C@]1(COP(O)(O)=O)CC[C@@H](C1)c1ccc2C[C@H](CSCCc3ccncc3)CCc2c1 |r| Show InChI InChI=1S/C24H33N2O4PS/c25-24(17-30-31(27,28)29)9-5-23(15-24)22-4-3-20-13-19(1-2-21(20)14-22)16-32-12-8-18-6-10-26-11-7-18/h3-4,6-7,10-11,14,19,23H,1-2,5,8-9,12-13,15-17,25H2,(H2,27,28,29)/t19-,23+,24-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	<10	n/a	n/a	n/a	37
Bristol-Myers Squibb Company US Patent					Assay Description hS1P1/CHO cells were plated into BD Amine 384-well plates the day before the assay. On the day of the assay, growth medium was removed and replaced w...				US Patent US9522888 (2016) BindingDB Entry DOI: 10.7270/Q20K27HV
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM65179 (US10166249, Example 525 | US9522888, 525) Show SMILES N[C@]1(COP(O)(O)=O)CC[C@@H](C1)c1ccc2C[C@H](CSCCc3ccncc3)CCc2c1 |r| Show InChI InChI=1S/C24H33N2O4PS/c25-24(17-30-31(27,28)29)9-5-23(15-24)22-4-3-20-13-19(1-2-21(20)14-22)16-32-12-8-18-6-10-26-11-7-18/h3-4,6-7,10-11,14,19,23H,1-2,5,8-9,12-13,15-17,25H2,(H2,27,28,29)/t19-,23+,24-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	55	n/a	n/a	n/a	60
Bristol-Myers Squibb Company US Patent					Assay Description Compounds were loaded in a 384 Falcon v-bottom plate (0.5 ul/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG3-Gal...				US Patent US9522888 (2016) BindingDB Entry DOI: 10.7270/Q20K27HV
					More data for this Ligand-Target Pair
Sphingosine-1-phosphate lyase 1 (Homo sapiens (Human))	BDBM65179 (US10166249, Example 525 | US9522888, 525) Show SMILES N[C@]1(COP(O)(O)=O)CC[C@@H](C1)c1ccc2C[C@H](CSCCc3ccncc3)CCc2c1 |r| Show InChI InChI=1S/C24H33N2O4PS/c25-24(17-30-31(27,28)29)9-5-23(15-24)22-4-3-20-13-19(1-2-21(20)14-22)16-32-12-8-18-6-10-26-11-7-18/h3-4,6-7,10-11,14,19,23H,1-2,5,8-9,12-13,15-17,25H2,(H2,27,28,29)/t19-,23+,24-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	55	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Compounds were loaded in a 384 Falcon v-bottom plate (0.5 l/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG3-Gal5...				US Patent US10166249 (2019) BindingDB Entry DOI: 10.7270/Q2S75JCM
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human))	BDBM65179 (US10166249, Example 525 | US9522888, 525) Show SMILES N[C@]1(COP(O)(O)=O)CC[C@@H](C1)c1ccc2C[C@H](CSCCc3ccncc3)CCc2c1 |r| Show InChI InChI=1S/C24H33N2O4PS/c25-24(17-30-31(27,28)29)9-5-23(15-24)22-4-3-20-13-19(1-2-21(20)14-22)16-32-12-8-18-6-10-26-11-7-18/h3-4,6-7,10-11,14,19,23H,1-2,5,8-9,12-13,15-17,25H2,(H2,27,28,29)/t19-,23+,24-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	>625	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Compounds were loaded in a 384 Falcon v-bottom plate (0.5 l/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG3-Gal5...				US Patent US10166249 (2019) BindingDB Entry DOI: 10.7270/Q2S75JCM
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human))	BDBM65179 (US10166249, Example 525 | US9522888, 525) Show SMILES N[C@]1(COP(O)(O)=O)CC[C@@H](C1)c1ccc2C[C@H](CSCCc3ccncc3)CCc2c1 |r| Show InChI InChI=1S/C24H33N2O4PS/c25-24(17-30-31(27,28)29)9-5-23(15-24)22-4-3-20-13-19(1-2-21(20)14-22)16-32-12-8-18-6-10-26-11-7-18/h3-4,6-7,10-11,14,19,23H,1-2,5,8-9,12-13,15-17,25H2,(H2,27,28,29)/t19-,23+,24-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	>625	n/a	n/a	n/a	60
Bristol-Myers Squibb Company US Patent					Assay Description Compounds were loaded in a 384 Falcon v-bottom plate (0.5 ul/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG3-Gal...				US Patent US9522888 (2016) BindingDB Entry DOI: 10.7270/Q20K27HV
					More data for this Ligand-Target Pair