Compile Data Set for Download or QSAR

Found 10 hits of ec50 for monomerid = 65316   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sphingosine-1-phosphate lyase 1 (Homo sapiens (Human))	BDBM65316 (US10166249, Example 633 | US9522888, 630) Show SMILES CCCCC1CCCC2(CCc3cc(ccc3C2)[C@H]2CC[C@](N)(COP(O)(O)=O)C2)O1 |r| Show InChI InChI=1S/C24H38NO5P/c1-2-3-5-22-6-4-11-24(30-22)13-10-19-14-18(7-8-20(19)16-24)21-9-12-23(25,15-21)17-29-31(26,27)28/h7-8,14,21-22H,2-6,9-13,15-17,25H2,1H3,(H2,26,27,28)/t21-,22?,23+,24?/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<10	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description hS1P1/CHO cells were plated into BD Amine 384-well plates the day before the assay. On the day of the assay, growth medium was removed and replaced w...				US Patent US10166249 (2019) BindingDB Entry DOI: 10.7270/Q2S75JCM
					More data for this Ligand-Target Pair
Sphingosine-1-phosphate lyase 1 (Homo sapiens (Human))	BDBM65316 (US10166249, Example 633 | US9522888, 630) Show SMILES CCCCC1CCCC2(CCc3cc(ccc3C2)[C@H]2CC[C@](N)(COP(O)(O)=O)C2)O1 |r| Show InChI InChI=1S/C24H38NO5P/c1-2-3-5-22-6-4-11-24(30-22)13-10-19-14-18(7-8-20(19)16-24)21-9-12-23(25,15-21)17-29-31(26,27)28/h7-8,14,21-22H,2-6,9-13,15-17,25H2,1H3,(H2,26,27,28)/t21-,22?,23+,24?/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<10	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description hS1P1/CHO cells were plated into BD Amine 384-well plates the day before the assay. On the day of the assay, growth medium was removed and replaced w...				US Patent US10166249 (2019) BindingDB Entry DOI: 10.7270/Q2S75JCM
					More data for this Ligand-Target Pair
Sphingosine-1-phosphate lyase 1 (Homo sapiens (Human))	BDBM65316 (US10166249, Example 633 | US9522888, 630) Show SMILES CCCCC1CCCC2(CCc3cc(ccc3C2)[C@H]2CC[C@](N)(COP(O)(O)=O)C2)O1 |r| Show InChI InChI=1S/C24H38NO5P/c1-2-3-5-22-6-4-11-24(30-22)13-10-19-14-18(7-8-20(19)16-24)21-9-12-23(25,15-21)17-29-31(26,27)28/h7-8,14,21-22H,2-6,9-13,15-17,25H2,1H3,(H2,26,27,28)/t21-,22?,23+,24?/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	55	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Compounds were loaded in a 384 Falcon v-bottom plate (0.5 l/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG3-Gal5...				US Patent US10166249 (2019) BindingDB Entry DOI: 10.7270/Q2S75JCM
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM65316 (US10166249, Example 633 | US9522888, 630) Show SMILES CCCCC1CCCC2(CCc3cc(ccc3C2)[C@H]2CC[C@](N)(COP(O)(O)=O)C2)O1 |r| Show InChI InChI=1S/C24H38NO5P/c1-2-3-5-22-6-4-11-24(30-22)13-10-19-14-18(7-8-20(19)16-24)21-9-12-23(25,15-21)17-29-31(26,27)28/h7-8,14,21-22H,2-6,9-13,15-17,25H2,1H3,(H2,26,27,28)/t21-,22?,23+,24?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	550	n/a	n/a	n/a	37
Bristol-Myers Squibb Company US Patent					Assay Description hS1P1/CHO cells were plated into BD Amine 384-well plates the day before the assay. On the day of the assay, growth medium was removed and replaced w...				US Patent US9522888 (2016) BindingDB Entry DOI: 10.7270/Q20K27HV
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human))	BDBM65316 (US10166249, Example 633 | US9522888, 630) Show SMILES CCCCC1CCCC2(CCc3cc(ccc3C2)[C@H]2CC[C@](N)(COP(O)(O)=O)C2)O1 |r| Show InChI InChI=1S/C24H38NO5P/c1-2-3-5-22-6-4-11-24(30-22)13-10-19-14-18(7-8-20(19)16-24)21-9-12-23(25,15-21)17-29-31(26,27)28/h7-8,14,21-22H,2-6,9-13,15-17,25H2,1H3,(H2,26,27,28)/t21-,22?,23+,24?/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>625	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Compounds were loaded in a 384 Falcon v-bottom plate (0.5 l/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG3-Gal5...				US Patent US10166249 (2019) BindingDB Entry DOI: 10.7270/Q2S75JCM
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human))	BDBM65316 (US10166249, Example 633 | US9522888, 630) Show SMILES CCCCC1CCCC2(CCc3cc(ccc3C2)[C@H]2CC[C@](N)(COP(O)(O)=O)C2)O1 |r| Show InChI InChI=1S/C24H38NO5P/c1-2-3-5-22-6-4-11-24(30-22)13-10-19-14-18(7-8-20(19)16-24)21-9-12-23(25,15-21)17-29-31(26,27)28/h7-8,14,21-22H,2-6,9-13,15-17,25H2,1H3,(H2,26,27,28)/t21-,22?,23+,24?/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>625	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Compounds were loaded in a 384 Falcon v-bottom plate (0.5 l/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG3-Gal5...				US Patent US10166249 (2019) BindingDB Entry DOI: 10.7270/Q2S75JCM
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human))	BDBM65316 (US10166249, Example 633 | US9522888, 630) Show SMILES CCCCC1CCCC2(CCc3cc(ccc3C2)[C@H]2CC[C@](N)(COP(O)(O)=O)C2)O1 |r| Show InChI InChI=1S/C24H38NO5P/c1-2-3-5-22-6-4-11-24(30-22)13-10-19-14-18(7-8-20(19)16-24)21-9-12-23(25,15-21)17-29-31(26,27)28/h7-8,14,21-22H,2-6,9-13,15-17,25H2,1H3,(H2,26,27,28)/t21-,22?,23+,24?/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>625	n/a	n/a	n/a	60
Bristol-Myers Squibb Company US Patent					Assay Description Compounds were loaded in a 384 Falcon v-bottom plate (0.5 ul/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG3-Gal...				US Patent US9522888 (2016) BindingDB Entry DOI: 10.7270/Q20K27HV
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human))	BDBM65316 (US10166249, Example 633 | US9522888, 630) Show SMILES CCCCC1CCCC2(CCc3cc(ccc3C2)[C@H]2CC[C@](N)(COP(O)(O)=O)C2)O1 |r| Show InChI InChI=1S/C24H38NO5P/c1-2-3-5-22-6-4-11-24(30-22)13-10-19-14-18(7-8-20(19)16-24)21-9-12-23(25,15-21)17-29-31(26,27)28/h7-8,14,21-22H,2-6,9-13,15-17,25H2,1H3,(H2,26,27,28)/t21-,22?,23+,24?/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>625	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Compounds were loaded in a 384 Falcon v-bottom plate (0.5 l/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG3-Gal5...				US Patent US10166249 (2019) BindingDB Entry DOI: 10.7270/Q2S75JCM
					More data for this Ligand-Target Pair
Sphingosine-1-phosphate lyase 1 (Homo sapiens (Human))	BDBM65316 (US10166249, Example 633 | US9522888, 630) Show SMILES CCCCC1CCCC2(CCc3cc(ccc3C2)[C@H]2CC[C@](N)(COP(O)(O)=O)C2)O1 |r| Show InChI InChI=1S/C24H38NO5P/c1-2-3-5-22-6-4-11-24(30-22)13-10-19-14-18(7-8-20(19)16-24)21-9-12-23(25,15-21)17-29-31(26,27)28/h7-8,14,21-22H,2-6,9-13,15-17,25H2,1H3,(H2,26,27,28)/t21-,22?,23+,24?/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Compounds were loaded in a 384 Falcon v-bottom plate (0.5 l/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG3-Gal5...				US Patent US10166249 (2019) BindingDB Entry DOI: 10.7270/Q2S75JCM
					More data for this Ligand-Target Pair
Sphingosine-1-phosphate lyase 1 (Homo sapiens (Human))	BDBM65316 (US10166249, Example 633 | US9522888, 630) Show SMILES CCCCC1CCCC2(CCc3cc(ccc3C2)[C@H]2CC[C@](N)(COP(O)(O)=O)C2)O1 |r| Show InChI InChI=1S/C24H38NO5P/c1-2-3-5-22-6-4-11-24(30-22)13-10-19-14-18(7-8-20(19)16-24)21-9-12-23(25,15-21)17-29-31(26,27)28/h7-8,14,21-22H,2-6,9-13,15-17,25H2,1H3,(H2,26,27,28)/t21-,22?,23+,24?/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description hS1P1/CHO cells were plated into BD Amine 384-well plates the day before the assay. On the day of the assay, growth medium was removed and replaced w...				US Patent US10166249 (2019) BindingDB Entry DOI: 10.7270/Q2S75JCM
					More data for this Ligand-Target Pair