Compile Data Set for Download or QSAR

Found 6 hits of ec50 for monomerid = 65356   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM65356 (US10166249, Example 665 | US9522888, 665) Show SMILES CCCCO\N=C(/C)[C@@H]1CCc2cc(ccc2C1)[C@H]1CC[C@](N)(COP(O)(O)=O)C1 |r| Show InChI InChI=1S/C22H35N2O5P/c1-3-4-11-28-24-16(2)17-5-6-19-13-20(8-7-18(19)12-17)21-9-10-22(23,14-21)15-29-30(25,26)27/h7-8,13,17,21H,3-6,9-12,14-15,23H2,1-2H3,(H2,25,26,27)/b24-16+/t17-,21+,22-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<10	n/a	n/a	n/a	60
Bristol-Myers Squibb Company US Patent					Assay Description Compounds were loaded in a 384 Falcon v-bottom plate (0.5 ul/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG3-Gal...				US Patent US9522888 (2016) BindingDB Entry DOI: 10.7270/Q20K27HV
					More data for this Ligand-Target Pair
Sphingosine-1-phosphate lyase 1 (Homo sapiens (Human))	BDBM65356 (US10166249, Example 665 | US9522888, 665) Show SMILES CCCCO\N=C(/C)[C@@H]1CCc2cc(ccc2C1)[C@H]1CC[C@](N)(COP(O)(O)=O)C1 |r| Show InChI InChI=1S/C22H35N2O5P/c1-3-4-11-28-24-16(2)17-5-6-19-13-20(8-7-18(19)12-17)21-9-10-22(23,14-21)15-29-30(25,26)27/h7-8,13,17,21H,3-6,9-12,14-15,23H2,1-2H3,(H2,25,26,27)/b24-16+/t17-,21+,22-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<10	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Compounds were loaded in a 384 Falcon v-bottom plate (0.5 l/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG3-Gal5...				US Patent US10166249 (2019) BindingDB Entry DOI: 10.7270/Q2S75JCM
					More data for this Ligand-Target Pair
Sphingosine-1-phosphate lyase 1 (Homo sapiens (Human))	BDBM65356 (US10166249, Example 665 | US9522888, 665) Show SMILES CCCCO\N=C(/C)[C@@H]1CCc2cc(ccc2C1)[C@H]1CC[C@](N)(COP(O)(O)=O)C1 |r| Show InChI InChI=1S/C22H35N2O5P/c1-3-4-11-28-24-16(2)17-5-6-19-13-20(8-7-18(19)12-17)21-9-10-22(23,14-21)15-29-30(25,26)27/h7-8,13,17,21H,3-6,9-12,14-15,23H2,1-2H3,(H2,25,26,27)/b24-16+/t17-,21+,22-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	55	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description hS1P1/CHO cells were plated into BD Amine 384-well plates the day before the assay. On the day of the assay, growth medium was removed and replaced w...				US Patent US10166249 (2019) BindingDB Entry DOI: 10.7270/Q2S75JCM
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM65356 (US10166249, Example 665 | US9522888, 665) Show SMILES CCCCO\N=C(/C)[C@@H]1CCc2cc(ccc2C1)[C@H]1CC[C@](N)(COP(O)(O)=O)C1 |r| Show InChI InChI=1S/C22H35N2O5P/c1-3-4-11-28-24-16(2)17-5-6-19-13-20(8-7-18(19)12-17)21-9-10-22(23,14-21)15-29-30(25,26)27/h7-8,13,17,21H,3-6,9-12,14-15,23H2,1-2H3,(H2,25,26,27)/b24-16+/t17-,21+,22-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	55	n/a	n/a	n/a	37
Bristol-Myers Squibb Company US Patent					Assay Description hS1P1/CHO cells were plated into BD Amine 384-well plates the day before the assay. On the day of the assay, growth medium was removed and replaced w...				US Patent US9522888 (2016) BindingDB Entry DOI: 10.7270/Q20K27HV
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human))	BDBM65356 (US10166249, Example 665 | US9522888, 665) Show SMILES CCCCO\N=C(/C)[C@@H]1CCc2cc(ccc2C1)[C@H]1CC[C@](N)(COP(O)(O)=O)C1 |r| Show InChI InChI=1S/C22H35N2O5P/c1-3-4-11-28-24-16(2)17-5-6-19-13-20(8-7-18(19)12-17)21-9-10-22(23,14-21)15-29-30(25,26)27/h7-8,13,17,21H,3-6,9-12,14-15,23H2,1-2H3,(H2,25,26,27)/b24-16+/t17-,21+,22-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>625	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Compounds were loaded in a 384 Falcon v-bottom plate (0.5 l/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG3-Gal5...				US Patent US10166249 (2019) BindingDB Entry DOI: 10.7270/Q2S75JCM
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human))	BDBM65356 (US10166249, Example 665 | US9522888, 665) Show SMILES CCCCO\N=C(/C)[C@@H]1CCc2cc(ccc2C1)[C@H]1CC[C@](N)(COP(O)(O)=O)C1 |r| Show InChI InChI=1S/C22H35N2O5P/c1-3-4-11-28-24-16(2)17-5-6-19-13-20(8-7-18(19)12-17)21-9-10-22(23,14-21)15-29-30(25,26)27/h7-8,13,17,21H,3-6,9-12,14-15,23H2,1-2H3,(H2,25,26,27)/b24-16+/t17-,21+,22-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>625	n/a	n/a	n/a	60
Bristol-Myers Squibb Company US Patent					Assay Description Compounds were loaded in a 384 Falcon v-bottom plate (0.5 ul/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG3-Gal...				US Patent US9522888 (2016) BindingDB Entry DOI: 10.7270/Q20K27HV
					More data for this Ligand-Target Pair