BindingDB PrimarySearch

Found 8 hits of ec50 for monomerid = 78304
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM78304 (2-(2-hydroxy-5-prop-2-enylphenyl)-4-prop-2-enylphe...) Show SMILES Oc1ccc(CC=C)cc1-c1cc(CC=C)ccc1O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid PDB UniChem Similars	PDB	n/a	n/a	n/a	n/a	458	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM78304 (2-(2-hydroxy-5-prop-2-enylphenyl)-4-prop-2-enylphe...) Show SMILES Oc1ccc(CC=C)cc1-c1cc(CC=C)ccc1O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid PDB UniChem Similars	PDB	n/a	n/a	n/a	n/a	1.62E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM78304 (2-(2-hydroxy-5-prop-2-enylphenyl)-4-prop-2-enylphe...) Show SMILES Oc1ccc(CC=C)cc1-c1cc(CC=C)ccc1O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.28E+3	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Partial agonist activity at recombinant human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation at 10...				ACS Med Chem Lett 4: 41-5 (2013) Article DOI: 10.1021/ml300235q BindingDB Entry DOI: 10.7270/Q2SF2XHW
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Homo sapiens (Human))	BDBM78304 (2-(2-hydroxy-5-prop-2-enylphenyl)-4-prop-2-enylphe...) Show SMILES Oc1ccc(CC=C)cc1-c1cc(CC=C)ccc1O Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jnatprod.1c00840 BindingDB Entry DOI: 10.7270/Q2K64P33
TBA					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM78304 (2-(2-hydroxy-5-prop-2-enylphenyl)-4-prop-2-enylphe...) Show SMILES Oc1ccc(CC=C)cc1-c1cc(CC=C)ccc1O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid PDB UniChem Similars		n/a	n/a	n/a	n/a	1.14E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM78304 (2-(2-hydroxy-5-prop-2-enylphenyl)-4-prop-2-enylphe...) Show SMILES Oc1ccc(CC=C)cc1-c1cc(CC=C)ccc1O Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.83E+4	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Partial agonist activity at recombinant human CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation at 10...				ACS Med Chem Lett 4: 41-5 (2013) Article DOI: 10.1021/ml300235q BindingDB Entry DOI: 10.7270/Q2SF2XHW
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2 (Homo sapiens (Human))	BDBM78304 (2-(2-hydroxy-5-prop-2-enylphenyl)-4-prop-2-enylphe...) Show SMILES Oc1ccc(CC=C)cc1-c1cc(CC=C)ccc1O Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.68E+4	n/a	n/a	n/a	n/a
University of Vienna Curated by ChEMBL					Assay Description Modulation of GABA Aalpha1beta2 receptor expressed in Xenopus laevis oocytes assessed as potentiation of GABA-induced chloride current at holding pot...				J Med Chem 54: 5349-61 (2011) Article DOI: 10.1021/jm200186n BindingDB Entry DOI: 10.7270/Q2QR4XGP
University of Vienna Curated by ChEMBL					More data for this Ligand-Target Pair
Aldehyde dehydrogenase, mitochondrial (Homo sapiens (Human))	BDBM78304 (2-(2-hydroxy-5-prop-2-enylphenyl)-4-prop-2-enylphe...) Show SMILES Oc1ccc(CC=C)cc1-c1cc(CC=C)ccc1O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.79E+4	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human recombinant ALDH2 measured after 1 hr				Citation and Details Article DOI: 10.1016/j.bmcl.2021.128045 BindingDB Entry DOI: 10.7270/Q2N301QC
TBA					More data for this Ligand-Target Pair