Compile Data Set for Download or QSAR

Found 3 hits of ic50 for monomerid = 109087   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM109087 (US10793535, Cmpd ID 671 | US8604016, 671 | US99382...) Show SMILES FC(F)(F)Oc1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)Cc4cccnc4)s3)nn2)c1 Show InChI InChI=1S/C26H24F3N7O3S/c27-26(28,29)39-20-8-3-5-17(13-20)14-22(37)31-21-11-10-19(33-34-21)7-1-2-9-24-35-36-25(40-24)32-23(38)15-18-6-4-12-30-16-18/h3-6,8,10-13,16H,1-2,7,9,14-15H2,(H,31,34,37)(H,32,36,38)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair
Glutamate dehydrogenase 2, mitochondrial (Human)	BDBM109087 (US10793535, Cmpd ID 671 | US8604016, 671 | US99382...) Show SMILES FC(F)(F)Oc1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)Cc4cccnc4)s3)nn2)c1 Show InChI InChI=1S/C26H24F3N7O3S/c27-26(28,29)39-20-8-3-5-17(13-20)14-22(37)31-21-11-10-19(33-34-21)7-1-2-9-24-35-36-25(40-24)32-23(38)15-18-6-4-12-30-16-18/h3-6,8,10-13,16H,1-2,7,9,14-15H2,(H,31,34,37)(H,32,36,38)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences, Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US10793535 (2020) BindingDB Entry DOI: 10.7270/Q2FJ2KV5
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM109087 (US10793535, Cmpd ID 671 | US8604016, 671 | US99382...) Show SMILES FC(F)(F)Oc1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)Cc4cccnc4)s3)nn2)c1 Show InChI InChI=1S/C26H24F3N7O3S/c27-26(28,29)39-20-8-3-5-17(13-20)14-22(37)31-21-11-10-19(33-34-21)7-1-2-9-24-35-36-25(40-24)32-23(38)15-18-6-4-12-30-16-18/h3-6,8,10-13,16H,1-2,7,9,14-15H2,(H,31,34,37)(H,32,36,38)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				J Med Chem 51: 1681-94 (2008) BindingDB Entry DOI: 10.7270/Q2JS9SQV
					More data for this Ligand-Target Pair