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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 120953   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histone deacetylase 8


(Homo sapiens (Human))
BDBM120953
PNG
(US8716285, 10)
Show SMILES ONC(=O)c1ccc2CCC(Cc2c1)Nc1nccc(n1)-c1ccccc1
Show InChI InChI=1S/C21H20N4O2/c26-20(25-27)16-7-6-14-8-9-18(13-17(14)12-16)23-21-22-11-10-19(24-21)15-4-2-1-3-5-15/h1-7,10-12,18,27H,8-9,13H2,(H,25,26)(H,22,23,24)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

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DrugBank
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PC cid
PC sid
UniChem
US Patent
n/an/a 2.13E+3n/an/an/an/an/an/a



Hoffmann-La Roche Inc.

US Patent


Assay Description
Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...


US Patent US8716285 (2014)


BindingDB Entry DOI: 10.7270/Q2K072XG
More data for this
Ligand-Target Pair