Compile Data Set for Download or QSAR

Found 2 hits of ic50 for monomerid = 12105   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase A (Homo sapiens (Human))	BDBM12105 (1,4,5,6-Tetrahydropyrrolo[3,4-c]pyrazole 13 | 4-te...) Show SMILES CC(C)(C)c1ccc(cc1)C(=O)Nc1[nH]nc2CN(Cc12)C(=O)Cc1ccccc1 Show InChI InChI=1S/C24H26N4O2/c1-24(2,3)18-11-9-17(10-12-18)23(30)25-22-19-14-28(15-20(19)26-27-22)21(29)13-16-7-5-4-6-8-16/h4-12H,13-15H2,1-3H3,(H2,25,26,27,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Vertex Pharmaceuticals (Europe) Ltd. Curated by ChEMBL					Assay Description Inhibition of aurora A kinase				J Med Chem 52: 2629-51 (2009) Checked by Author Article DOI: 10.1021/jm8012129 BindingDB Entry DOI: 10.7270/Q2B85920
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM12105 (1,4,5,6-Tetrahydropyrrolo[3,4-c]pyrazole 13 | 4-te...) Show SMILES CC(C)(C)c1ccc(cc1)C(=O)Nc1[nH]nc2CN(Cc12)C(=O)Cc1ccccc1 Show InChI InChI=1S/C24H26N4O2/c1-24(2,3)18-11-9-17(10-12-18)23(30)25-22-19-14-28(15-20(19)26-27-22)21(29)13-16-7-5-4-6-8-16/h4-12H,13-15H2,1-3H3,(H2,25,26,27,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	7.5	22
Nerviano Medical Sciences					Assay Description The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...				J Med Chem 48: 3080-4 (2005) Article DOI: 10.1021/jm049076m BindingDB Entry DOI: 10.7270/Q2FF3QKK
					More data for this Ligand-Target Pair