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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 140287   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase SYK


(Homo sapiens (Human))
BDBM140287
PNG
(US8912173, 13)
Show SMILES COc1cc(ccc1O)-c1cc(OC[C@H]2CNC(=O)O2)c2cccnc2c1 |r|
Show InChI InChI=1S/C20H18N2O5/c1-25-19-8-12(4-5-17(19)23)13-7-16-15(3-2-6-21-16)18(9-13)26-11-14-10-22-20(24)27-14/h2-9,14,23H,10-11H2,1H3,(H,22,24)/t14-/m1/s1
PDB
MMDB

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Similars

US Patent
n/an/a 1n/an/an/an/a7.5-80



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...


US Patent US8912173 (2014)


BindingDB Entry DOI: 10.7270/Q2TX3D3T
More data for this
Ligand-Target Pair