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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 144498   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase SYK


(Homo sapiens (Human))
BDBM144498
PNG
(US8969568, 50)
Show SMILES COC[C@H](C)Oc1ccc(cc1OC)-c1cc2ncccc2c(OC[C@H]2CNC(=O)C2)n1 |r|
Show InChI InChI=1S/C24H27N3O5/c1-15(13-29-2)32-21-7-6-17(10-22(21)30-3)19-11-20-18(5-4-8-25-20)24(27-19)31-14-16-9-23(28)26-12-16/h4-8,10-11,15-16H,9,12-14H2,1-3H3,(H,26,28)/t15-,16+/m0/s1
PDB
MMDB

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Similars

US Patent
n/an/a 2.70n/an/an/an/an/an/a



Boehringer Ingelheim Pharma GmbH & Co. KG

US Patent


Assay Description
Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...


US Patent US8969568 (2015)


BindingDB Entry DOI: 10.7270/Q2154FRD
More data for this
Ligand-Target Pair