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Compile Data Set for Download or QSAR

Found 2 hits of ic50 for monomerid = 151291   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Endothelial lipase


(Homo sapiens (Human))
BDBM151291
PNG
(US8987314, B87)
Show SMILES COc1ccc(cn1)-c1ccc2sc(nc2c1)C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O
Show InChI InChI=1S/C18H20N4O6S3/c1-28-15-6-4-12(10-21-15)11-3-5-14-13(9-11)22-18(29-14)16(30(2,24)25)17(23)20-7-8-31(19,26)27/h3-6,9-10,16H,7-8H2,1-2H3,(H,20,23)(H2,19,26,27)
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 0.5n/an/an/an/a8.025



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)


BindingDB Entry DOI: 10.7270/Q2W094N8
More data for this
Ligand-Target Pair
Hepatic triacylglycerol lipase


(Homo sapiens (Human))
BDBM151291
PNG
(US8987314, B87)
Show SMILES COc1ccc(cn1)-c1ccc2sc(nc2c1)C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O
Show InChI InChI=1S/C18H20N4O6S3/c1-28-15-6-4-12(10-21-15)11-3-5-14-13(9-11)22-18(29-14)16(30(2,24)25)17(23)20-7-8-31(19,26)27/h3-6,9-10,16H,7-8H2,1-2H3,(H,20,23)(H2,19,26,27)
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 2.60n/an/an/an/a8.025



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)


BindingDB Entry DOI: 10.7270/Q2W094N8
More data for this
Ligand-Target Pair