Found 4 hits of ic50 for monomerid = 15203 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
cAMP-dependent protein kinase catalytic subunit gamma
(Homo sapiens (Human)) | BDBM15203
(5-(piperazine-1-sulfonyl)isoquinoline | CHEMBL7577...)Show InChI InChI=1S/C13H15N3O2S/c17-19(18,16-8-6-14-7-9-16)13-3-1-2-11-10-15-5-4-12(11)13/h1-5,10,14H,6-9H2 | KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
URA CNRS 1309
Curated by ChEMBL
| Assay Description Inhibition of cAMP-dependent protein kinase (PKA). |
J Med Chem 34: 73-8 (1991)
BindingDB Entry DOI: 10.7270/Q2J38VS9 |
More data for this Ligand-Target Pair | |
O94806/P05129/P05771/P17252/P24723/P41743/Q02156/Q04759/Q05513/Q05655/Q15139
(Homo sapiens (Human)) | BDBM15203
(5-(piperazine-1-sulfonyl)isoquinoline | CHEMBL7577...)Show InChI InChI=1S/C13H15N3O2S/c17-19(18,16-8-6-14-7-9-16)13-3-1-2-11-10-15-5-4-12(11)13/h1-5,10,14H,6-9H2 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
URA CNRS 1309
Curated by ChEMBL
| Assay Description Inhibition of protein kinase C (PKC) |
J Med Chem 34: 73-8 (1991)
BindingDB Entry DOI: 10.7270/Q2J38VS9 |
More data for this Ligand-Target Pair | |
RAC-beta serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM15203
(5-(piperazine-1-sulfonyl)isoquinoline | CHEMBL7577...)Show InChI InChI=1S/C13H15N3O2S/c17-19(18,16-8-6-14-7-9-16)13-3-1-2-11-10-15-5-4-12(11)13/h1-5,10,14H,6-9H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.30E+4 | n/a | n/a | n/a | n/a | 7.2 | 22 |
UK Centre for Cancer Therapeutics
| Assay Description The purified PKB beta enzyme was assayed with a peptide substrate and test compound in the presence of 30 uM ATP/ [gamma-33P]ATP in 96-well plates. I... |
Bioorg Med Chem 14: 1255-73 (2006)
Article DOI: 10.1016/j.bmc.2005.09.055 BindingDB Entry DOI: 10.7270/Q2FN14F2 |
More data for this Ligand-Target Pair | |
MO15-related protein kinase Pfmrk
(Plasmodium falciparum) | BDBM15203
(5-(piperazine-1-sulfonyl)isoquinoline | CHEMBL7577...)Show InChI InChI=1S/C13H15N3O2S/c17-19(18,16-8-6-14-7-9-16)13-3-1-2-11-10-15-5-4-12(11)13/h1-5,10,14H,6-9H2 | UniProtKB/TrEMBL
GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >5.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Research
Curated by ChEMBL
| Assay Description Inhibition of Plasmodium falciparum Pfmrk |
Bioorg Med Chem Lett 17: 4961-6 (2007)
Article DOI: 10.1016/j.bmcl.2007.06.032 BindingDB Entry DOI: 10.7270/Q2GX4CC8 |
More data for this Ligand-Target Pair | |