Compile Data Set for Download or QSAR

Found 3 hits of ic50 for monomerid = 161453   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM161453 (US10124003, Ex. Compound 66 | US10835536, Ex. Comp...) Show SMILES COC(=O)[C@@H]1C[C@@H](CN1C(=O)C=C)n1cc(C#Cc2cc(OC)cc(OC)c2)c2c(N)ncnc12 |r| Show InChI InChI=1S/C25H25N5O5/c1-5-21(31)30-13-17(10-20(30)25(32)35-4)29-12-16(22-23(26)27-14-28-24(22)29)7-6-15-8-18(33-2)11-19(9-15)34-3/h5,8-9,11-12,14,17,20H,1,10,13H2,2-4H3,(H2,26,27,28)/t17-,20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<0.300	n/a	n/a	n/a	n/a	7.5	25
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...				US Patent US9108973 (2015) BindingDB Entry DOI: 10.7270/Q2XW4HJV
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM161453 (US10124003, Ex. Compound 66 | US10835536, Ex. Comp...) Show SMILES COC(=O)[C@@H]1C[C@@H](CN1C(=O)C=C)n1cc(C#Cc2cc(OC)cc(OC)c2)c2c(N)ncnc12 |r| Show InChI InChI=1S/C25H25N5O5/c1-5-21(31)30-13-17(10-20(30)25(32)35-4)29-12-16(22-23(26)27-14-28-24(22)29)7-6-15-8-18(33-2)11-19(9-15)34-3/h5,8-9,11-12,14,17,20H,1,10,13H2,2-4H3,(H2,26,27,28)/t17-,20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<0.300	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...				US Patent US10835536 (2020) BindingDB Entry DOI: 10.7270/Q23N26F5
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM161453 (US10124003, Ex. Compound 66 | US10835536, Ex. Comp...) Show SMILES COC(=O)[C@@H]1C[C@@H](CN1C(=O)C=C)n1cc(C#Cc2cc(OC)cc(OC)c2)c2c(N)ncnc12 |r| Show InChI InChI=1S/C25H25N5O5/c1-5-21(31)30-13-17(10-20(30)25(32)35-4)29-12-16(22-23(26)27-14-28-24(22)29)7-6-15-8-18(33-2)11-19(9-15)34-3/h5,8-9,11-12,14,17,20H,1,10,13H2,2-4H3,(H2,26,27,28)/t17-,20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<0.300	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...				US Patent US10124003 (2018) BindingDB Entry DOI: 10.7270/Q2B27XBQ
					More data for this Ligand-Target Pair