Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Voltage-dependent T-type calcium channel subunit alpha-1G (Homo sapiens (Human)) | BDBM164208 (US9688615, 19) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.5 | n/a | n/a | n/a | n/a | n/a | n/a |
SRMLSC US Patent | Assay Description Cells were plated in 384-well, clear-bottom, black-walled, poly-D-lysine coated plates (Becton Dickinson, Franklin Lake, N.J.) 2 days prior to use in... | US Patent US9688615 (2017) BindingDB Entry DOI: 10.7270/Q27S7KXH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human)) | BDBM164208 (US9688615, 19) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
SRMLSC US Patent | Assay Description Cells were plated in 384-well, clear-bottom, black-walled, poly-D-lysine coated plates (Becton Dickinson, Franklin Lake, N.J.) 2 days prior to use in... | US Patent US9688615 (2017) BindingDB Entry DOI: 10.7270/Q27S7KXH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human)) | BDBM164208 (US9688615, 19) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 530 | n/a | n/a | n/a | n/a | n/a | n/a |
SRMLSC US Patent | Assay Description Cells were plated in 384-well, clear-bottom, black-walled, poly-D-lysine coated plates (Becton Dickinson, Franklin Lake, N.J.) 2 days prior to use in... | US Patent US9688615 (2017) BindingDB Entry DOI: 10.7270/Q27S7KXH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human)) | BDBM164208 (US9688615, 19) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.94E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
SRMLSC US Patent | Assay Description Cells were plated in 384-well, clear-bottom, black-walled, poly-D-lysine coated plates (Becton Dickinson, Franklin Lake, N.J.) 2 days prior to use in... | US Patent US9688615 (2017) BindingDB Entry DOI: 10.7270/Q27S7KXH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1C (Homo sapiens (Human)) | BDBM164208 (US9688615, 19) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.56E+3 | n/a | n/a | n/a | n/a | 7.4 | n/a |
SRMLSC US Patent | Assay Description To assess the potential cardiac liability of compounds at an early stage in the drug discovery process, a Nav1.5 sodium channel screening assay was b... | US Patent US9688615 (2017) BindingDB Entry DOI: 10.7270/Q27S7KXH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1C (Homo sapiens (Human)) | BDBM164208 (US9688615, 19) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 6.12E+3 | n/a | n/a | n/a | n/a | 7.4 | n/a |
SRMLSC US Patent | Assay Description To assess the potential cardiac liability of compounds at an early stage in the drug discovery process, a Nav1.5 sodium channel screening assay was b... | US Patent US9688615 (2017) BindingDB Entry DOI: 10.7270/Q27S7KXH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human)) | BDBM164208 (US9688615, 19) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
SRMLSC US Patent | Assay Description Cells were plated in 384-well, clear-bottom, black-walled, poly-D-lysine coated plates (Becton Dickinson, Franklin Lake, N.J.) 2 days prior to use in... | US Patent US9688615 (2017) BindingDB Entry DOI: 10.7270/Q27S7KXH | |||||||||||
More data for this Ligand-Target Pair |