BindingDB PrimarySearch

Found 16 hits of ic50 for monomerid = 164901
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
BDNF/NT-3 growth factors receptor (Homo sapiens (Human))	BDBM164901 (US10166239, Ex. 3-15 \| US11406644, Example 3-15 \| ...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
GENZYME CORPORATION US Patent					Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...				US Patent US9611265 (2017) BindingDB Entry DOI: 10.7270/Q2S184KD
GENZYME CORPORATION US Patent					More data for this Ligand-Target Pair
BDNF/NT-3 growth factors receptor (Homo sapiens (Human))	BDBM164901 (US10166239, Ex. 3-15 \| US11406644, Example 3-15 \| ...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CV4MZ5
TBA					More data for this Ligand-Target Pair
BDNF/NT-3 growth factors receptor (Homo sapiens (Human))	BDBM164901 (US10166239, Ex. 3-15 \| US11406644, Example 3-15 \| ...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
Genzyme Corporation US Patent					Assay Description In a 384 well polypropylene plate, TrkB (0.6 nM, Carna 08-187) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ...				US Patent US10166239 (2019) BindingDB Entry DOI: 10.7270/Q2WW7KSN
Genzyme Corporation US Patent					More data for this Ligand-Target Pair
BDNF/NT-3 growth factors receptor (Homo sapiens (Human))	BDBM164901 (US10166239, Ex. 3-15 \| US11406644, Example 3-15 \| ...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.100	n/a	n/a	n/a	n/a	7.5	25
Genzyme Corporation US Patent					Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...				US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB
Genzyme Corporation US Patent					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM164901 (US10166239, Ex. 3-15 \| US11406644, Example 3-15 \| ...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	7.5	25
Genzyme Corporation US Patent					Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...				US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB
Genzyme Corporation US Patent					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM164901 (US10166239, Ex. 3-15 \| US11406644, Example 3-15 \| ...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
GENZYME CORPORATION US Patent					Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...				US Patent US9611265 (2017) BindingDB Entry DOI: 10.7270/Q2S184KD
GENZYME CORPORATION US Patent					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM164901 (US10166239, Ex. 3-15 \| US11406644, Example 3-15 \| ...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Genzyme Corporation US Patent					Assay Description In a 384 well polypropylene plate, TrkA (0.4 nM, Carna 08-186) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ...				US Patent US10166239 (2019) BindingDB Entry DOI: 10.7270/Q2WW7KSN
Genzyme Corporation US Patent					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM164901 (US10166239, Ex. 3-15 \| US11406644, Example 3-15 \| ...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CV4MZ5
TBA					More data for this Ligand-Target Pair
NT-3 growth factor receptor (Homo sapiens (Human))	BDBM164901 (US10166239, Ex. 3-15 \| US11406644, Example 3-15 \| ...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.503	n/a	n/a	n/a	n/a	n/a	n/a
GENZYME CORPORATION US Patent					Assay Description Human TrkC, catalytic domain [456-825(end) amino acids of accession number NP_002521.2] was expressed as N-terminal GST-fusion protein (69 kDa) using...				US Patent US9611265 (2017) BindingDB Entry DOI: 10.7270/Q2S184KD
GENZYME CORPORATION US Patent					More data for this Ligand-Target Pair
NT-3 growth factor receptor (Homo sapiens (Human))	BDBM164901 (US10166239, Ex. 3-15 \| US11406644, Example 3-15 \| ...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.503	n/a	n/a	n/a	n/a	n/a	n/a
Genzyme Corporation US Patent					Assay Description Human TrkC, catalytic domain [456-825(end) amino acids of accession number NP_002521.2] was expressed as N-terminal GST-fusion protein (69 kDa) using...				US Patent US10166239 (2019) BindingDB Entry DOI: 10.7270/Q2WW7KSN
Genzyme Corporation US Patent					More data for this Ligand-Target Pair
NT-3 growth factor receptor (Homo sapiens (Human))	BDBM164901 (US10166239, Ex. 3-15 \| US11406644, Example 3-15 \| ...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.503	n/a	n/a	n/a	n/a	n/a	n/a
Genzyme Corporation US Patent					Assay Description Human TrkC, catalytic domain [456-825(end) amino acids of accession number NP-002521.2] was expressed as N-terminal GST-fusion protein (69 kDa) using...				US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB
Genzyme Corporation US Patent					More data for this Ligand-Target Pair
NT-3 growth factor receptor (Homo sapiens (Human))	BDBM164901 (US10166239, Ex. 3-15 \| US11406644, Example 3-15 \| ...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.503	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Human TrkC, catalytic domain [456-825 (end) amino acids of accession number NP_002521.2] was expressed as N-terminal GST-fusion protein (69 kDa) usin...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CV4MZ5
TBA					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM164901 (US10166239, Ex. 3-15 \| US11406644, Example 3-15 \| ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Genzyme Corporation US Patent					Assay Description In a 384 well polypropylene plate, c-FMS (0.14 nM, Carna 08-155) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100...				US Patent US10166239 (2019) BindingDB Entry DOI: 10.7270/Q2WW7KSN
Genzyme Corporation US Patent					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM164901 (US10166239, Ex. 3-15 \| US11406644, Example 3-15 \| ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	25
Genzyme Corporation US Patent					Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...				US Patent US9067914 (2015) BindingDB Entry DOI: 10.7270/Q28051CB
Genzyme Corporation US Patent					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM164901 (US10166239, Ex. 3-15 \| US11406644, Example 3-15 \| ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CV4MZ5
TBA					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM164901 (US10166239, Ex. 3-15 \| US11406644, Example 3-15 \| ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
GENZYME CORPORATION US Patent					Assay Description Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...				US Patent US9611265 (2017) BindingDB Entry DOI: 10.7270/Q2S184KD
GENZYME CORPORATION US Patent					More data for this Ligand-Target Pair