Compile Data Set for Download or QSAR

Found 2 hits of ic50 for monomerid = 16537   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-alpha serine/threonine-protein kinase [139-480,S378A,S381A,T450D,S473D] (Homo sapiens (Human))	BDBM16537 ((2S)-1-(2,3-difluorophenyl)-3-{[5-(3-methyl-1H-ind...) Show SMILES Cc1n[nH]c2ccc(cc12)-c1cncc(OC[C@@H](N)Cc2cccc(F)c2F)c1 |r| Show InChI InChI=1S/C22H20F2N4O/c1-13-19-9-14(5-6-21(19)28-27-13)16-8-18(11-26-10-16)29-12-17(25)7-15-3-2-4-20(23)22(15)24/h2-6,8-11,17H,7,12,25H2,1H3,(H,27,28)/t17-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.5	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...				J Med Chem 50: 2990-3003 (2007) Article DOI: 10.1021/jm0701019 BindingDB Entry DOI: 10.7270/Q24X562F
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase catalytic subunit alpha (Bos taurus (bovine))	BDBM16537 ((2S)-1-(2,3-difluorophenyl)-3-{[5-(3-methyl-1H-ind...) Show SMILES Cc1n[nH]c2ccc(cc12)-c1cncc(OC[C@@H](N)Cc2cccc(F)c2F)c1 |r| Show InChI InChI=1S/C22H20F2N4O/c1-13-19-9-14(5-6-21(19)28-27-13)16-8-18(11-26-10-16)29-12-17(25)7-15-3-2-4-20(23)22(15)24/h2-6,8-11,17H,7,12,25H2,1H3,(H,27,28)/t17-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description The kinase assay uses purified recombinant enzyme and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidi...				J Med Chem 50: 2990-3003 (2007) Article DOI: 10.1021/jm0701019 BindingDB Entry DOI: 10.7270/Q24X562F
					More data for this Ligand-Target Pair