Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 16573   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-alpha serine/threonine-protein kinase [139-480,S378A,S381A,T450D,S473D] (Homo sapiens (Human))	BDBM16573 ((2S)-1-{[5-(3-methyl-1H-indazol-5-yl)pyridin-3-yl]...) Show SMILES Cc1n[nH]c2ccc(cc12)-c1cncc(OC[C@@H](N)Cc2cccc(OC(F)(F)F)c2)c1 |r| Show InChI InChI=1S/C23H21F3N4O2/c1-14-21-10-16(5-6-22(21)30-29-14)17-9-20(12-28-11-17)31-13-18(27)7-15-3-2-4-19(8-15)32-23(24,25)26/h2-6,8-12,18H,7,13,27H2,1H3,(H,29,30)/t18-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...				J Med Chem 50: 2990-3003 (2007) Article DOI: 10.1021/jm0701019 BindingDB Entry DOI: 10.7270/Q24X562F
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