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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Peptidyl-prolyl cis-trans isomerase A (Homo sapiens (Human)) | BDBM172718 (US11802108, Compound CSA | US9090657, Cyclosporine...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet  | Purchase KEGG PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 9.70 | n/a | n/a | n/a | n/a | n/a | n/a |
NEUROVIVE PHARMACEUTICAL AB US Patent | Assay Description The PPlase activity of recombinant CypA or D, produced by thrombin cleavage of GST-CypA or D, was determined by following the rate of hydrolysis of N... | US Patent US9090657 (2015) BindingDB Entry DOI: 10.7270/Q22Z148H | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Solute carrier organic anion transporter family member 1B3 (Homo sapiens (Human)) | BDBM172718 (US11802108, Compound CSA | US9090657, Cyclosporine...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase KEGG PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 130 | n/a | n/a | n/a | n/a | 7.3 | 37 |
NEUROVIVE PHARMACEUTICAL AB US Patent | Assay Description To assess the inhibition of the OAT1B1 and OAT1B3 uptake transporters, an in vitro uptake transporter assay from Solvo Biotechnology Inc. was used. U... | US Patent US9090657 (2015) BindingDB Entry DOI: 10.7270/Q22Z148H | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Bile salt export pump (Homo sapiens (Human)) | BDBM172718 (US11802108, Compound CSA | US9090657, Cyclosporine...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase KEGG PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 460 | n/a | n/a | n/a | n/a | n/a | 37 |
NEUROVIVE PHARMACEUTICAL AB US Patent | Assay Description To assess the inhibition of the MRP2, MRP3 and BSEP efflux transporters, an in vitro vesicular transporter assay from Solvo Biotechnology Inc. was us... | US Patent US9090657 (2015) BindingDB Entry DOI: 10.7270/Q22Z148H | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| ATP-dependent translocase ABCB1 (Homo sapiens (Human)) | BDBM172718 (US11802108, Compound CSA | US9090657, Cyclosporine...) | PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase KEGG PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 730 | n/a | n/a | n/a | n/a | 7.4 | 37 |
NEUROVIVE PHARMACEUTICAL AB US Patent | Assay Description To assess the inhibition of the P-glycoprotein (Pgp/MDR1) transporter, an in vitro ATPase assay from Cyprotex was used. MDR1MDCK cells obtained from ... | US Patent US9090657 (2015) BindingDB Entry DOI: 10.7270/Q22Z148H | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Solute carrier organic anion transporter family member 1B1 (Homo sapiens (Human)) | BDBM172718 (US11802108, Compound CSA | US9090657, Cyclosporine...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase KEGG PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 850 | n/a | n/a | n/a | n/a | 7.3 | 37 |
NEUROVIVE PHARMACEUTICAL AB US Patent | Assay Description To assess the inhibition of the OAT1B1 and OAT1B3 uptake transporters, an in vitro uptake transporter assay from Solvo Biotechnology Inc. was used. U... | US Patent US9090657 (2015) BindingDB Entry DOI: 10.7270/Q22Z148H | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| ATP-binding cassette sub-family C member 2 (Homo sapiens (Human)) | BDBM172718 (US11802108, Compound CSA | US9090657, Cyclosporine...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase KEGG PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3.10E+3 | n/a | n/a | n/a | n/a | n/a | 37 |
NEUROVIVE PHARMACEUTICAL AB US Patent | Assay Description To assess the inhibition of the MRP2, MRP3 and BSEP efflux transporters, an in vitro vesicular transporter assay from Solvo Biotechnology Inc. was us... | US Patent US9090657 (2015) BindingDB Entry DOI: 10.7270/Q22Z148H | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| ATP-binding cassette sub-family C member 2 (Homo sapiens (Human)) | BDBM172718 (US11802108, Compound CSA | US9090657, Cyclosporine...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase KEGG PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 4.10E+3 | n/a | n/a | n/a | n/a | n/a | 37 |
NEUROVIVE PHARMACEUTICAL AB US Patent | Assay Description To assess the inhibition of the MRP2, MRP3 and BSEP efflux transporters, an in vitro vesicular transporter assay from Solvo Biotechnology Inc. was us... | US Patent US9090657 (2015) BindingDB Entry DOI: 10.7270/Q22Z148H | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
