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Compile Data Set for Download or QSAR

Found 2 hits of ic50 for monomerid = 17660   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cystine/glutamate transporter


(Homo sapiens (Human))
BDBM17660
PNG
((2S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl...)
Show SMILES N[C@@H](Cn1oc(=O)[nH]c1=O)C(O)=O
Show InChI InChI=1S/C5H7N3O5/c6-2(3(9)10)1-8-4(11)7-5(12)13-8/h2H,1,6H2,(H,9,10)(H,7,11,12)/t2-/m0/s1
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KEGG
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PC cid
PC sid
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Article
PubMed
n/an/a 5.00E+3n/an/an/an/an/an/a



The University of Montana

Curated by ChEMBL


Assay Description
Inhibition of amino acid transport system xc-


Bioorg Med Chem Lett 20: 2680-3 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.020
BindingDB Entry DOI: 10.7270/Q29Z952F
More data for this
Ligand-Target Pair
Glutamate Carboxypeptidase II (GCPII)


(Homo sapiens (Human))
BDBM17660
PNG
((2S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl...)
Show SMILES N[C@@H](Cn1oc(=O)[nH]c1=O)C(O)=O
Show InChI InChI=1S/C5H7N3O5/c6-2(3(9)10)1-8-4(11)7-5(12)13-8/h2H,1,6H2,(H,9,10)(H,7,11,12)/t2-/m0/s1
PDB
MMDB

KEGG

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CHEMBL
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PC cid
PC sid
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UniChem

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PDB
Article
PubMed
n/an/a 9.50E+3n/an/an/an/a7.437



NCI-FCRDC



Assay Description
The inhibition concentration values of GCPII were determined using the radioenzymatic assay with [3H] NAAG (radiolabeled on the terminal glutamate). ...


J Med Chem 50: 3267-73 (2007)


Article DOI: 10.1021/jm070133w
BindingDB Entry DOI: 10.7270/Q29C6VPS
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)