Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 21924   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 8 (Homo sapiens (Human))	BDBM21924 (2-({8-chloro-4-[(3-chloro-4-fluorophenyl)amino]-3-...) Show SMILES Fc1ccc(Nc2c(cnc3c(Cl)cc(NCC(=O)Nc4cccnc4)cc23)C#N)cc1Cl Show InChI InChI=1S/C23H15Cl2FN6O/c24-18-7-14(3-4-20(18)26)32-22-13(9-27)10-30-23-17(22)6-16(8-19(23)25)29-12-21(33)31-15-2-1-5-28-11-15/h1-8,10-11,29H,12H2,(H,30,32)(H,31,33)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	7.2	30
Wyeth Research					Assay Description Tpl2/Cot activity was directly assayed using GST-MEK1 as a substrate. The phosphorylation on serine residues was detected by an ELISA. IC50 calculati...				J Med Chem 50: 4728-45 (2007) Article DOI: 10.1021/jm070436q BindingDB Entry DOI: 10.7270/Q2891441
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