Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 21939   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 8 (Homo sapiens (Human))	BDBM21939 (8-bromo-4-[(3-chloro-4-fluorophenyl)amino]-6-({[1-...) Show SMILES CS(=O)(=O)CCn1cnc(CNc2cc(Br)c3ncc(C#N)c(Nc4ccc(F)c(Cl)c4)c3c2)c1 Show InChI InChI=1S/C23H19BrClFN6O2S/c1-35(33,34)5-4-32-12-17(30-13-32)11-28-16-6-18-22(31-15-2-3-21(26)20(25)8-15)14(9-27)10-29-23(18)19(24)7-16/h2-3,6-8,10,12-13,28H,4-5,11H2,1H3,(H,29,31)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Tpl2/Cot activity was directly assayed using GST-MEK1 as a substrate. The phosphorylation on serine residues was detected by an ELISA. IC50 calculati...				J Med Chem 50: 4728-45 (2007) Article DOI: 10.1021/jm070436q BindingDB Entry DOI: 10.7270/Q2891441
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