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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 221949   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cystic fibrosis transmembrane conductance regulator


(Cricetulus griseus (Chinese hamster))		BDBM221949
PNG
(US9303035, 1.17)
Show SMILES Cn1c2c3C(NCCn3c(-c3ccccc3)c2c(=O)n(C)c1=O)C1CCC=CC1 |c:30|
Show InChI InChI=1S/C23H26N4O2/c1-25-20-17(22(28)26(2)23(25)29)19(16-11-7-4-8-12-16)27-14-13-24-18(21(20)27)15-9-5-3-6-10-15/h3-5,7-8,11-12,15,18,24H,6,9-10,13-14H2,1-2H3
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 18.1n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh...

US Patent US9303035 (2016)


BindingDB Entry DOI: 10.7270/Q2SQ8Z7R
More data for this
Ligand-Target Pair