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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 221994   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cystic fibrosis transmembrane conductance regulator


(Cricetulus griseus (Chinese hamster))		BDBM221994
PNG
(US9303035, 12.5)
Show SMILES Cn1c2c3C(OC(C)(C)Cn3c(-c3ccccc3)c2c(=O)n(C)c1=O)c1ccc(Cl)o1
Show InChI InChI=1S/C23H22ClN3O4/c1-23(2)12-27-17(13-8-6-5-7-9-13)16-18(25(3)22(29)26(4)21(16)28)19(27)20(31-23)14-10-11-15(24)30-14/h5-11,20H,12H2,1-4H3
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.620n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh...

US Patent US9303035 (2016)


BindingDB Entry DOI: 10.7270/Q2SQ8Z7R
More data for this
Ligand-Target Pair