Compile Data Set for Download or QSAR

Found 3 hits of ic50 for monomerid = 223091   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM223091 (2-(Dimethylamino)ethyl 4-(6-((5-((2-chloro-6-methy...) Show SMILES CN(C)CCOC(=O)N1CCN(CC1)c1cc(Nc2ncc(s2)C(=O)Nc2c(C)cccc2Cl)nc(C)n1 Show InChI InChI=1S/C25H31ClN8O3S/c1-16-6-5-7-18(26)22(16)31-23(35)19-15-27-24(38-19)30-20-14-21(29-17(2)28-20)33-8-10-34(11-9-33)25(36)37-13-12-32(3)4/h5-7,14-15H,8-13H2,1-4H3,(H,31,35)(H,27,28,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.105	n/a	n/a	n/a	n/a	7.5	25
Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences					Assay Description ABL activity assays were performed in 384-well plate using the FRET-based Z'-Lyteassay system and Tyr-2 peptide substrate according to the manufa...				Chem Biol Drug Des 89: 420-427 (2017) Article DOI: 10.1111/cbdd.12863 BindingDB Entry DOI: 10.7270/Q29C6W98
					More data for this Ligand-Target Pair
Epithelial discoidin domain-containing receptor 1 (Homo sapiens (Human))	BDBM223091 (2-(Dimethylamino)ethyl 4-(6-((5-((2-chloro-6-methy...) Show SMILES CN(C)CCOC(=O)N1CCN(CC1)c1cc(Nc2ncc(s2)C(=O)Nc2c(C)cccc2Cl)nc(C)n1 Show InChI InChI=1S/C25H31ClN8O3S/c1-16-6-5-7-18(26)22(16)31-23(35)19-15-27-24(38-19)30-20-14-21(29-17(2)28-20)33-8-10-34(11-9-33)25(36)37-13-12-32(3)4/h5-7,14-15H,8-13H2,1-4H3,(H,31,35)(H,27,28,29,30)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.56	n/a	n/a	n/a	n/a	7.5	25
Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences					Assay Description The effects of compounds on the kinases DDR1 and DDR2 were assessed by using a LanthaScreen Eu kinase activity assay technology (Invitrogen, Carlsbad...				Chem Biol Drug Des 89: 420-427 (2017) Article DOI: 10.1111/cbdd.12863 BindingDB Entry DOI: 10.7270/Q29C6W98
					More data for this Ligand-Target Pair
Discoidin domain-containing receptor 2 (Homo sapiens (Human))	BDBM223091 (2-(Dimethylamino)ethyl 4-(6-((5-((2-chloro-6-methy...) Show SMILES CN(C)CCOC(=O)N1CCN(CC1)c1cc(Nc2ncc(s2)C(=O)Nc2c(C)cccc2Cl)nc(C)n1 Show InChI InChI=1S/C25H31ClN8O3S/c1-16-6-5-7-18(26)22(16)31-23(35)19-15-27-24(38-19)30-20-14-21(29-17(2)28-20)33-8-10-34(11-9-33)25(36)37-13-12-32(3)4/h5-7,14-15H,8-13H2,1-4H3,(H,31,35)(H,27,28,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.89	n/a	n/a	n/a	n/a	7.5	25
Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences					Assay Description The effects of compounds on the kinases DDR1 and DDR2 were assessed by using a LanthaScreen Eu kinase activity assay technology (Invitrogen, Carlsbad...				Chem Biol Drug Des 89: 420-427 (2017) Article DOI: 10.1111/cbdd.12863 BindingDB Entry DOI: 10.7270/Q29C6W98
					More data for this Ligand-Target Pair