Compile Data Set for Download or QSAR

Found 3 hits of ic50 for monomerid = 223099   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM223099 (Isobutyl 3-(6-((5-((2-chloro-6-methylphenyl)carbam...) Show SMILES CC(C)COC(=O)N1CCC(C1)c1cc(Nc2ncc(s2)C(=O)Nc2c(C)cccc2Cl)nc(C)n1 Show InChI InChI=1S/C25H29ClN6O3S/c1-14(2)13-35-25(34)32-9-8-17(12-32)19-10-21(29-16(4)28-19)30-24-27-11-20(36-24)23(33)31-22-15(3)6-5-7-18(22)26/h5-7,10-11,14,17H,8-9,12-13H2,1-4H3,(H,31,33)(H,27,28,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.602	n/a	n/a	n/a	n/a	7.5	25
Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences					Assay Description ABL activity assays were performed in 384-well plate using the FRET-based Z'-Lyteassay system and Tyr-2 peptide substrate according to the manufa...				Chem Biol Drug Des 89: 420-427 (2017) Article DOI: 10.1111/cbdd.12863 BindingDB Entry DOI: 10.7270/Q29C6W98
					More data for this Ligand-Target Pair
Epithelial discoidin domain-containing receptor 1 (Homo sapiens (Human))	BDBM223099 (Isobutyl 3-(6-((5-((2-chloro-6-methylphenyl)carbam...) Show SMILES CC(C)COC(=O)N1CCC(C1)c1cc(Nc2ncc(s2)C(=O)Nc2c(C)cccc2Cl)nc(C)n1 Show InChI InChI=1S/C25H29ClN6O3S/c1-14(2)13-35-25(34)32-9-8-17(12-32)19-10-21(29-16(4)28-19)30-24-27-11-20(36-24)23(33)31-22-15(3)6-5-7-18(22)26/h5-7,10-11,14,17H,8-9,12-13H2,1-4H3,(H,31,33)(H,27,28,29,30)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	12.1	n/a	n/a	n/a	n/a	7.5	25
Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences					Assay Description The effects of compounds on the kinases DDR1 and DDR2 were assessed by using a LanthaScreen Eu kinase activity assay technology (Invitrogen, Carlsbad...				Chem Biol Drug Des 89: 420-427 (2017) Article DOI: 10.1111/cbdd.12863 BindingDB Entry DOI: 10.7270/Q29C6W98
					More data for this Ligand-Target Pair
Discoidin domain-containing receptor 2 (Homo sapiens (Human))	BDBM223099 (Isobutyl 3-(6-((5-((2-chloro-6-methylphenyl)carbam...) Show SMILES CC(C)COC(=O)N1CCC(C1)c1cc(Nc2ncc(s2)C(=O)Nc2c(C)cccc2Cl)nc(C)n1 Show InChI InChI=1S/C25H29ClN6O3S/c1-14(2)13-35-25(34)32-9-8-17(12-32)19-10-21(29-16(4)28-19)30-24-27-11-20(36-24)23(33)31-22-15(3)6-5-7-18(22)26/h5-7,10-11,14,17H,8-9,12-13H2,1-4H3,(H,31,33)(H,27,28,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	85.4	n/a	n/a	n/a	n/a	7.5	25
Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences					Assay Description The effects of compounds on the kinases DDR1 and DDR2 were assessed by using a LanthaScreen Eu kinase activity assay technology (Invitrogen, Carlsbad...				Chem Biol Drug Des 89: 420-427 (2017) Article DOI: 10.1111/cbdd.12863 BindingDB Entry DOI: 10.7270/Q29C6W98
					More data for this Ligand-Target Pair