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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 226465   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine kinase receptor A (TrkA)


(Homo sapiens (Human))
BDBM226465
PNG
(US9328096, 158)
Show SMILES Cc1ncc(CNC(=O)c2cc(NC(=O)c3cc(c(Cl)cc3Cl)-c3ncccc3F)n(n2)-c2ccccc2)[nH]1
Show InChI InChI=1S/C27H20Cl2FN7O2/c1-15-32-13-16(34-15)14-33-27(39)23-12-24(37(36-23)17-6-3-2-4-7-17)35-26(38)19-10-18(20(28)11-21(19)29)25-22(30)8-5-9-31-25/h2-13H,14H2,1H3,(H,32,34)(H,33,39)(H,35,38)
PDB

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 4.71n/an/an/an/an/a37



Pfizer Inc.

US Patent


Assay Description
TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...


US Patent US9328096 (2016)


BindingDB Entry DOI: 10.7270/Q2FN152J
More data for this
Ligand-Target Pair