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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 226481   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
High affinity nerve growth factor receptor [441-796]


(Homo sapiens (Human))
BDBM226481
PNG
(US9328096, 174)
Show SMILES Fc1cccnc1-c1cc(C(=O)Nc2cc(nn2-c2ccccc2)C(=O)NCc2cn[nH]n2)c(Cl)cc1Cl
Show InChI InChI=1S/C25H17Cl2FN8O2/c26-18-10-19(27)17(9-16(18)23-20(28)7-4-8-29-23)24(37)32-22-11-21(25(38)30-12-14-13-31-35-33-14)34-36(22)15-5-2-1-3-6-15/h1-11,13H,12H2,(H,30,38)(H,32,37)(H,31,33,35)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.53n/an/an/an/an/a37



Pfizer Inc.

US Patent


Assay Description
TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...


US Patent US9328096 (2016)


BindingDB Entry DOI: 10.7270/Q2FN152J
More data for this
Ligand-Target Pair