BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 227058   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
High affinity nerve growth factor receptor [441-796]


(Homo sapiens (Human))
BDBM227058
PNG
(US9328096, 746)
Show SMILES Fc1cccnc1-c1cc(C(=O)Nc2cc(nn2-c2ccccc2)C(=O)NCCC#N)c(Cl)cc1Cl
Show InChI InChI=1S/C25H17Cl2FN6O2/c26-18-13-19(27)17(12-16(18)23-20(28)8-4-10-30-23)24(35)32-22-14-21(25(36)31-11-5-9-29)33-34(22)15-6-2-1-3-7-15/h1-4,6-8,10,12-14H,5,11H2,(H,31,36)(H,32,35)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3.25n/an/an/an/an/a37



Pfizer Inc.

US Patent


Assay Description
TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...


US Patent US9328096 (2016)


BindingDB Entry DOI: 10.7270/Q2FN152J
More data for this
Ligand-Target Pair