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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 227148   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
High affinity nerve growth factor receptor [441-796]


(Homo sapiens (Human))
BDBM227148
PNG
(US9328096, 836)
Show SMILES Nc1cc(CNC(=O)c2cc(NC(=O)c3cc(c(F)cc3Cl)-c3ncccc3F)n(n2)-c2ccccc2)ccn1
Show InChI InChI=1S/C28H20ClF2N7O2/c29-20-13-22(31)19(26-21(30)7-4-9-34-26)12-18(20)27(39)36-25-14-23(37-38(25)17-5-2-1-3-6-17)28(40)35-15-16-8-10-33-24(32)11-16/h1-14H,15H2,(H2,32,33)(H,35,40)(H,36,39)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.04n/an/an/an/an/a37



Pfizer Inc.

US Patent


Assay Description
TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...


US Patent US9328096 (2016)


BindingDB Entry DOI: 10.7270/Q2FN152J
More data for this
Ligand-Target Pair