Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Gamma-aminobutyric acid receptor subunit gamma-1 (Rattus norvegicus) | BDBM23183 (5-(aminomethyl)-1,2-oxazol-3-ol | Agarin | CHEMBL2...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents | PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibition of [3H]-GABA binding to Gamma-aminobutyric-acid receptor of rat brain synaptic membranes | J Med Chem 28: 1612-7 (1985) BindingDB Entry DOI: 10.7270/Q2PN94NZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid receptor subunit alpha-1 (Rattus norvegicus (Rat)) | BDBM23183 (5-(aminomethyl)-1,2-oxazol-3-ol | Agarin | CHEMBL2...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Urbino Carlo Bo Curated by ChEMBL | Assay Description Inhibitory concentration against human Adenosine A3 receptor expressed in HEK293 cells using 0.1 nM [3H]AB-MECA | J Med Chem 48: 6887-96 (2005) Article DOI: 10.1021/jm058018d BindingDB Entry DOI: 10.7270/Q28C9X1X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-amino-acid oxidase (Sus scrofa (pig)) | BDBM23183 (5-(aminomethyl)-1,2-oxazol-3-ol | Agarin | CHEMBL2...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | 8.5 | 22 |
MGI Pharma | Assay Description D-amino acid oxidase (DAAO) was assayed in a 96-well plate format. D-serine was oxidatively deaminated by porcine D-amino acid oxidase in the presenc... | J Med Chem 51: 3357-9 (2008) Article DOI: 10.1021/jm800200u BindingDB Entry DOI: 10.7270/Q21G0JJJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent GABA transporter 1/GABA transporter 2/GABA transporter 3/betaine transporter (Rattus norvegicus) | BDBM23183 (5-(aminomethyl)-1,2-oxazol-3-ol | Agarin | CHEMBL2...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents | PubMed | n/a | n/a | 3.20E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibition of GABA uptake in rat brain synaptic membranes | J Med Chem 28: 1612-7 (1985) BindingDB Entry DOI: 10.7270/Q2PN94NZ | |||||||||||
More data for this Ligand-Target Pair |