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Compile Data Set for Download or QSAR

Found 3 hits of ic50 for monomerid = 2484   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Reverse transcriptase/RNaseH


(Human immunodeficiency virus 1)
BDBM2484
PNG
(1-(benzenesulfonyl)-2-nitrobenzene | 2-nitrophenyl...)
Show SMILES [O-][N+](=O)c1ccccc1S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C12H9NO4S/c14-13(15)11-8-4-5-9-12(11)18(16,17)10-6-2-1-3-7-10/h1-9H
PDB
MMDB

UniProtKB/TrEMBL

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MCE
PC cid
PC sid
UniChem

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Article
PubMed
n/an/a 1.58E+4n/an/an/an/an/an/a



University of Perugia

Curated by ChEMBL


Assay Description
Inhibitory concentration against Reverse transcriptase


J Med Chem 48: 3756-67 (2005)


Article DOI: 10.1021/jm049162m
BindingDB Entry DOI: 10.7270/Q2XS5WQ0
More data for this
Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147]


(Human immunodeficiency virus type 1)
BDBM2484
PNG
(1-(benzenesulfonyl)-2-nitrobenzene | 2-nitrophenyl...)
Show SMILES [O-][N+](=O)c1ccccc1S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C12H9NO4S/c14-13(15)11-8-4-5-9-12(11)18(16,17)10-6-2-1-3-7-10/h1-9H
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
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MCE
PC cid
PC sid
UniChem

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Article
PubMed
n/an/a 1.60E+4n/an/an/an/an/an/a



GlaxoSmithKline



Assay Description
The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.


J Med Chem 44: 1866-82 (2001)


Article DOI: 10.1021/jm0004906
BindingDB Entry DOI: 10.7270/Q2FJ2F09
More data for this
Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147]


(Human immunodeficiency virus type 1)
BDBM2484
PNG
(1-(benzenesulfonyl)-2-nitrobenzene | 2-nitrophenyl...)
Show SMILES [O-][N+](=O)c1ccccc1S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C12H9NO4S/c14-13(15)11-8-4-5-9-12(11)18(16,17)10-6-2-1-3-7-10/h1-9H
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

MCE
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 5.05E+4n/an/an/an/a7.937



Universita degli Studi di Roma La Sapienza



Assay Description
The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.


J Med Chem 46: 2482-93 (2003)


Article DOI: 10.1021/jm0211063
BindingDB Entry DOI: 10.7270/Q2BP0101
More data for this
Ligand-Target Pair