Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Insulin receptor (Homo sapiens (Human)) | BDBM2580 (K252a | methyl (15R,16S,18S)-16-hydroxy-15-methyl-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 210 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Merck Research Laboratories | Assay Description The assay uses purified enzyme interacting with biotinylated peptide substrate.HTRF is based on the proximity of europium cryptate (donor fluorophore... | Biochemistry 44: 9430-40 (2005) Article DOI: 10.1021/bi0500628 BindingDB Entry DOI: 10.7270/Q2BV7DV5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-like growth factor 1 receptor (Homo sapiens (Human)) | BDBM2580 (K252a | methyl (15R,16S,18S)-16-hydroxy-15-methyl-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 470 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Merck Research Laboratories | Assay Description The assay uses purified enzyme interacting with biotinylated peptide substrate.HTRF is based on the proximity of europium cryptate (donor fluorophore... | Biochemistry 44: 9430-40 (2005) Article DOI: 10.1021/bi0500628 BindingDB Entry DOI: 10.7270/Q2BV7DV5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C beta type (Rattus norvegicus (rat)) | BDBM2580 (K252a | methyl (15R,16S,18S)-16-hydroxy-15-methyl-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 470 | n/a | n/a | n/a | n/a | 7.5 | 30 |
Roche Products Limited | Assay Description The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his... | J Med Chem 35: 177-84 (1992) Article DOI: 10.1021/jm00079a024 BindingDB Entry DOI: 10.7270/Q2K64G8V | |||||||||||
More data for this Ligand-Target Pair |