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Compile Data Set for Download or QSAR

Found 3 hits of ic50 for monomerid = 26187   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Carbonic anhydrase 3 (CA III)


(Bos taurus (Cattle))
BDBM26187
PNG
(α-CA inhibitor, 11 | CHEMBL14060 | US9688816,...)
Show SMILES Oc1ccccc1
Show InChI InChI=1S/C6H6O/c7-6-4-2-1-3-5-6/h1-5,7H
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Article
PubMed
n/an/a 4.63E+3n/an/an/an/a7.4n/a



Ondokuz Mayis University



Assay Description
The CA activity was assayed by following the change in absorbance at 348 nm of 4-NPA to 4-nitrophenylate ion over a period of 3 min at 25C using a s...


J Enzyme Inhib Med Chem 27: 845-8 (2012)


Article DOI: 10.3109/14756366.2011.621122
BindingDB Entry DOI: 10.7270/Q27P8X9X
More data for this
Ligand-Target Pair
Estradiol receptor beta (ERβ)


(Homo sapiens (Human))
BDBM26187
PNG
(α-CA inhibitor, 11 | CHEMBL14060 | US9688816,...)
Show SMILES Oc1ccccc1
Show InChI InChI=1S/C6H6O/c7-6-4-2-1-3-5-6/h1-5,7H
PDB

UniProtKB/SwissProt

antibodypedia
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CHEMBL
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KEGG
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PC cid
PC sid
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Patents

US Patent
n/an/a>2.50E+5n/an/an/an/an/an/a



SABIC GLOBAL TECHNOLOGIES B.V.

US Patent


Assay Description
Competitive binding assays were performed by incubating rhER alpha (α) and beta 1 (β1) receptors with 10 nM [3H]estradiol (the radio ligand...


US Patent US9688816 (2017)


BindingDB Entry DOI: 10.7270/Q2WD3XR0
More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))
BDBM26187
PNG
(α-CA inhibitor, 11 | CHEMBL14060 | US9688816,...)
Show SMILES Oc1ccccc1
Show InChI InChI=1S/C6H6O/c7-6-4-2-1-3-5-6/h1-5,7H
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents

US Patent
n/an/a>2.50E+5n/an/an/an/an/an/a



SABIC GLOBAL TECHNOLOGIES B.V.

US Patent


Assay Description
Competitive binding assays were performed by incubating rhER alpha (α) and beta 1 (β1) receptors with 10 nM [3H]estradiol (the radio ligand...


US Patent US9688816 (2017)


BindingDB Entry DOI: 10.7270/Q2WD3XR0
More data for this
Ligand-Target Pair