BindingDB PrimarySearch

Found 8 hits of ic50 for monomerid = 26189
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM26189 (α-CA inhibitor, 13 \| 1,3-Dihydroxybenzene, XI...) Show SMILES Oc1cccc(O)c1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania School of Medicine Curated by ChEMBL					Assay Description Inhibition of peroxidase activity of COX1 in heep seminal vesicle by TMPD assay				J Nat Prod 67: 1777-82 (2004) Article DOI: 10.1021/np0498410 BindingDB Entry DOI: 10.7270/Q2XD12JH
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM26189 (α-CA inhibitor, 13 \| 1,3-Dihydroxybenzene, XI...) Show SMILES Oc1cccc(O)c1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	3.08E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania School of Medicine Curated by ChEMBL					Assay Description Inhibition of cyclooxygenase activity of COX1 in sheep seminal vesicle in presence of 1 mM phenol by cyclooxygenase assay				J Nat Prod 67: 1777-82 (2004) Article DOI: 10.1021/np0498410 BindingDB Entry DOI: 10.7270/Q2XD12JH
					More data for this Ligand-Target Pair
Estrogen receptor beta (Homo sapiens (Human))	BDBM26189 (α-CA inhibitor, 13 \| 1,3-Dihydroxybenzene, XI...) Show SMILES Oc1cccc(O)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	US Patent	n/a	n/a	>2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
SABIC GLOBAL TECHNOLOGIES B.V. US Patent					Assay Description Competitive binding assays were performed by incubating rhER alpha (α) and beta 1 (β1) receptors with 10 nM [3H]estradiol (the radio ligand...				US Patent US9688816 (2017) BindingDB Entry DOI: 10.7270/Q2WD3XR0
SABIC GLOBAL TECHNOLOGIES B.V. US Patent					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM26189 (α-CA inhibitor, 13 \| 1,3-Dihydroxybenzene, XI...) Show SMILES Oc1cccc(O)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	US Patent	n/a	n/a	>2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
SABIC GLOBAL TECHNOLOGIES B.V. US Patent					Assay Description Competitive binding assays were performed by incubating rhER alpha (α) and beta 1 (β1) receptors with 10 nM [3H]estradiol (the radio ligand...				US Patent US9688816 (2017) BindingDB Entry DOI: 10.7270/Q2WD3XR0
SABIC GLOBAL TECHNOLOGIES B.V. US Patent					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM26189 (α-CA inhibitor, 13 \| 1,3-Dihydroxybenzene, XI...) Show SMILES Oc1cccc(O)c1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	6.52E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Murcia Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase using L-dopa as substrate assessed as diphenolase activity by spectrophotometric analysis				Bioorg Med Chem 24: 4434-4443 (2016) Article DOI: 10.1016/j.bmc.2016.07.048 BindingDB Entry DOI: 10.7270/Q24F1SP6
University of Murcia Curated by ChEMBL					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM26189 (α-CA inhibitor, 13 \| 1,3-Dihydroxybenzene, XI...) Show SMILES Oc1cccc(O)c1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.13E+6	n/a	n/a	n/a	n/a	n/a	n/a
University of Murcia Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase using L-tyrosine as substrate assessed as monophenolase activity by spectrophotometric analysis				Bioorg Med Chem 24: 4434-4443 (2016) Article DOI: 10.1016/j.bmc.2016.07.048 BindingDB Entry DOI: 10.7270/Q24F1SP6
University of Murcia Curated by ChEMBL					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM26189 (α-CA inhibitor, 13 \| 1,3-Dihydroxybenzene, XI...) Show SMILES Oc1cccc(O)c1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.44E+6	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Cagliari Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosine kinase assessed as oxidation of 0.25 mM L-3,4-dihydroxyphenylalanine				Bioorg Med Chem Lett 19: 36-9 (2008) Article DOI: 10.1016/j.bmcl.2008.11.020 BindingDB Entry DOI: 10.7270/Q2445MB2
Università degli Studi di Cagliari Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosinase (Homo sapiens (Human))	BDBM26189 (α-CA inhibitor, 13 \| 1,3-Dihydroxybenzene, XI...) Show SMILES Oc1cccc(O)c1 Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>3.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human His-tagged tyrosinase expressed in HEK 293 cells using L-DOPA as substrate by MBTH based assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00994 BindingDB Entry DOI: 10.7270/Q2PV6Q29
TBA					More data for this Ligand-Target Pair