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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 269021   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine/threonine-protein kinase Sgk1


(Homo sapiens (Human))
BDBM269021
PNG
(US9718825, Example 464)
Show SMILES Cc1nc(nc2[nH]nc(N)c12)-c1ccc(NS(=O)(=O)c2cc(Cl)ccc2Cl)cc1
Show InChI InChI=1S/C18H14Cl2N6O2S/c1-9-15-16(21)24-25-18(15)23-17(22-9)10-2-5-12(6-3-10)26-29(27,28)14-8-11(19)4-7-13(14)20/h2-8,26H,1H3,(H3,21,22,23,24,25)
PDB
MMDB

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PC cid
PC sid
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US Patent
n/an/a<1.20n/an/an/an/a7.4n/a



SANOFI

US Patent


Assay Description
The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...


US Patent US9718825 (2017)


BindingDB Entry DOI: 10.7270/Q2VM4F82
More data for this
Ligand-Target Pair