Compile Data Set for Download or QSAR

Found 6 hits of ic50 for monomerid = 273385   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 7 (Homo sapiens (Human))	BDBM273385 (US10071079, Example 168 | US10478424, Example 168) Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CCS(N)(=O)=O)CC1)-c1cc(C)c2ncnn2c1 Show InChI InChI=1S/C25H32N6O2S/c1-16(2)23-21-13-19(18-6-8-30(9-7-18)10-11-34(26,32)33)4-5-22(21)29-24(23)20-12-17(3)25-27-15-28-31(25)14-20/h4-5,12-16,18,29H,6-11H2,1-3H3,(H2,26,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM273385 (US10071079, Example 168 | US10478424, Example 168) Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CCS(N)(=O)=O)CC1)-c1cc(C)c2ncnn2c1 Show InChI InChI=1S/C25H32N6O2S/c1-16(2)23-21-13-19(18-6-8-30(9-7-18)10-11-34(26,32)33)4-5-22(21)29-24(23)20-12-17(3)25-27-15-28-31(25)14-20/h4-5,12-16,18,29H,6-11H2,1-3H3,(H2,26,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10478424 (2019) BindingDB Entry DOI: 10.7270/Q2QZ2DB0
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Homo sapiens (Human))	BDBM273385 (US10071079, Example 168 | US10478424, Example 168) Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CCS(N)(=O)=O)CC1)-c1cc(C)c2ncnn2c1 Show InChI InChI=1S/C25H32N6O2S/c1-16(2)23-21-13-19(18-6-8-30(9-7-18)10-11-34(26,32)33)4-5-22(21)29-24(23)20-12-17(3)25-27-15-28-31(25)14-20/h4-5,12-16,18,29H,6-11H2,1-3H3,(H2,26,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10478424 (2019) BindingDB Entry DOI: 10.7270/Q2QZ2DB0
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Homo sapiens (Human))	BDBM273385 (US10071079, Example 168 | US10478424, Example 168) Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CCS(N)(=O)=O)CC1)-c1cc(C)c2ncnn2c1 Show InChI InChI=1S/C25H32N6O2S/c1-16(2)23-21-13-19(18-6-8-30(9-7-18)10-11-34(26,32)33)4-5-22(21)29-24(23)20-12-17(3)25-27-15-28-31(25)14-20/h4-5,12-16,18,29H,6-11H2,1-3H3,(H2,26,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair
Toll-like receptor 9 (Homo sapiens (Human))	BDBM273385 (US10071079, Example 168 | US10478424, Example 168) Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CCS(N)(=O)=O)CC1)-c1cc(C)c2ncnn2c1 Show InChI InChI=1S/C25H32N6O2S/c1-16(2)23-21-13-19(18-6-8-30(9-7-18)10-11-34(26,32)33)4-5-22(21)29-24(23)20-12-17(3)25-27-15-28-31(25)14-20/h4-5,12-16,18,29H,6-11H2,1-3H3,(H2,26,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.41E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10478424 (2019) BindingDB Entry DOI: 10.7270/Q2QZ2DB0
					More data for this Ligand-Target Pair
Toll-like receptor 9 (Homo sapiens (Human))	BDBM273385 (US10071079, Example 168 | US10478424, Example 168) Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CCS(N)(=O)=O)CC1)-c1cc(C)c2ncnn2c1 Show InChI InChI=1S/C25H32N6O2S/c1-16(2)23-21-13-19(18-6-8-30(9-7-18)10-11-34(26,32)33)4-5-22(21)29-24(23)20-12-17(3)25-27-15-28-31(25)14-20/h4-5,12-16,18,29H,6-11H2,1-3H3,(H2,26,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.41E+3	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair