Compile Data Set for Download or QSAR

Found 6 hits of ic50 for monomerid = 273477   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 7 (Homo sapiens (Human))	BDBM273477 (US10071079, Example 260 | US10478424, Example 260) Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CC(=O)N(C)C)CC1)-c1cc(Cl)c2nc(C)nn2c1 Show InChI InChI=1S/C27H33ClN6O/c1-16(2)25-21-12-19(18-8-10-33(11-9-18)15-24(35)32(4)5)6-7-23(21)30-26(25)20-13-22(28)27-29-17(3)31-34(27)14-20/h6-7,12-14,16,18,30H,8-11,15H2,1-5H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM273477 (US10071079, Example 260 | US10478424, Example 260) Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CC(=O)N(C)C)CC1)-c1cc(Cl)c2nc(C)nn2c1 Show InChI InChI=1S/C27H33ClN6O/c1-16(2)25-21-12-19(18-8-10-33(11-9-18)15-24(35)32(4)5)6-7-23(21)30-26(25)20-13-22(28)27-29-17(3)31-34(27)14-20/h6-7,12-14,16,18,30H,8-11,15H2,1-5H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10478424 (2019) BindingDB Entry DOI: 10.7270/Q2QZ2DB0
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Homo sapiens (Human))	BDBM273477 (US10071079, Example 260 | US10478424, Example 260) Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CC(=O)N(C)C)CC1)-c1cc(Cl)c2nc(C)nn2c1 Show InChI InChI=1S/C27H33ClN6O/c1-16(2)25-21-12-19(18-8-10-33(11-9-18)15-24(35)32(4)5)6-7-23(21)30-26(25)20-13-22(28)27-29-17(3)31-34(27)14-20/h6-7,12-14,16,18,30H,8-11,15H2,1-5H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13.9	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10478424 (2019) BindingDB Entry DOI: 10.7270/Q2QZ2DB0
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Homo sapiens (Human))	BDBM273477 (US10071079, Example 260 | US10478424, Example 260) Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CC(=O)N(C)C)CC1)-c1cc(Cl)c2nc(C)nn2c1 Show InChI InChI=1S/C27H33ClN6O/c1-16(2)25-21-12-19(18-8-10-33(11-9-18)15-24(35)32(4)5)6-7-23(21)30-26(25)20-13-22(28)27-29-17(3)31-34(27)14-20/h6-7,12-14,16,18,30H,8-11,15H2,1-5H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13.9	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair
Toll-like receptor 9 (Homo sapiens (Human))	BDBM273477 (US10071079, Example 260 | US10478424, Example 260) Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CC(=O)N(C)C)CC1)-c1cc(Cl)c2nc(C)nn2c1 Show InChI InChI=1S/C27H33ClN6O/c1-16(2)25-21-12-19(18-8-10-33(11-9-18)15-24(35)32(4)5)6-7-23(21)30-26(25)20-13-22(28)27-29-17(3)31-34(27)14-20/h6-7,12-14,16,18,30H,8-11,15H2,1-5H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10478424 (2019) BindingDB Entry DOI: 10.7270/Q2QZ2DB0
					More data for this Ligand-Target Pair
Toll-like receptor 9 (Homo sapiens (Human))	BDBM273477 (US10071079, Example 260 | US10478424, Example 260) Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CC(=O)N(C)C)CC1)-c1cc(Cl)c2nc(C)nn2c1 Show InChI InChI=1S/C27H33ClN6O/c1-16(2)25-21-12-19(18-8-10-33(11-9-18)15-24(35)32(4)5)6-7-23(21)30-26(25)20-13-22(28)27-29-17(3)31-34(27)14-20/h6-7,12-14,16,18,30H,8-11,15H2,1-5H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair