Compile Data Set for Download or QSAR

Found 6 hits of ic50 for monomerid = 273929   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 7 (Homo sapiens (Human))	BDBM273929 (US10071079, Example 715 | US10478424, Example 715) Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CC1)C(=O)CN(CCO)C1CC1)-c1cc(C)c2ncnn2c1 Show InChI InChI=1S/C30H38N6O2/c1-19(2)28-25-15-22(21-8-10-34(11-9-21)27(38)17-35(12-13-37)24-5-6-24)4-7-26(25)33-29(28)23-14-20(3)30-31-18-32-36(30)16-23/h4,7,14-16,18-19,21,24,33,37H,5-6,8-13,17H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM273929 (US10071079, Example 715 | US10478424, Example 715) Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CC1)C(=O)CN(CCO)C1CC1)-c1cc(C)c2ncnn2c1 Show InChI InChI=1S/C30H38N6O2/c1-19(2)28-25-15-22(21-8-10-34(11-9-21)27(38)17-35(12-13-37)24-5-6-24)4-7-26(25)33-29(28)23-14-20(3)30-31-18-32-36(30)16-23/h4,7,14-16,18-19,21,24,33,37H,5-6,8-13,17H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10478424 (2019) BindingDB Entry DOI: 10.7270/Q2QZ2DB0
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Homo sapiens (Human))	BDBM273929 (US10071079, Example 715 | US10478424, Example 715) Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CC1)C(=O)CN(CCO)C1CC1)-c1cc(C)c2ncnn2c1 Show InChI InChI=1S/C30H38N6O2/c1-19(2)28-25-15-22(21-8-10-34(11-9-21)27(38)17-35(12-13-37)24-5-6-24)4-7-26(25)33-29(28)23-14-20(3)30-31-18-32-36(30)16-23/h4,7,14-16,18-19,21,24,33,37H,5-6,8-13,17H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10478424 (2019) BindingDB Entry DOI: 10.7270/Q2QZ2DB0
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Homo sapiens (Human))	BDBM273929 (US10071079, Example 715 | US10478424, Example 715) Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CC1)C(=O)CN(CCO)C1CC1)-c1cc(C)c2ncnn2c1 Show InChI InChI=1S/C30H38N6O2/c1-19(2)28-25-15-22(21-8-10-34(11-9-21)27(38)17-35(12-13-37)24-5-6-24)4-7-26(25)33-29(28)23-14-20(3)30-31-18-32-36(30)16-23/h4,7,14-16,18-19,21,24,33,37H,5-6,8-13,17H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair
Toll-like receptor 9 (Homo sapiens (Human))	BDBM273929 (US10071079, Example 715 | US10478424, Example 715) Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CC1)C(=O)CN(CCO)C1CC1)-c1cc(C)c2ncnn2c1 Show InChI InChI=1S/C30H38N6O2/c1-19(2)28-25-15-22(21-8-10-34(11-9-21)27(38)17-35(12-13-37)24-5-6-24)4-7-26(25)33-29(28)23-14-20(3)30-31-18-32-36(30)16-23/h4,7,14-16,18-19,21,24,33,37H,5-6,8-13,17H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10478424 (2019) BindingDB Entry DOI: 10.7270/Q2QZ2DB0
					More data for this Ligand-Target Pair
Toll-like receptor 9 (Homo sapiens (Human))	BDBM273929 (US10071079, Example 715 | US10478424, Example 715) Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CC1)C(=O)CN(CCO)C1CC1)-c1cc(C)c2ncnn2c1 Show InChI InChI=1S/C30H38N6O2/c1-19(2)28-25-15-22(21-8-10-34(11-9-21)27(38)17-35(12-13-37)24-5-6-24)4-7-26(25)33-29(28)23-14-20(3)30-31-18-32-36(30)16-23/h4,7,14-16,18-19,21,24,33,37H,5-6,8-13,17H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.26E+3	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair