Compile Data Set for Download or QSAR

Found 6 hits of ic50 for monomerid = 274105   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 7 (Homo sapiens (Human))	BDBM274105 (US10071079, Example 891 | US10478424, Example 891) Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CC1)C(=O)CCNCC(N)=O)-c1cn2ncnc2c(C)c1C Show InChI InChI=1S/C29H37N7O2/c1-17(2)27-22-13-21(20-8-11-35(12-9-20)26(38)7-10-31-14-25(30)37)5-6-24(22)34-28(27)23-15-36-29(32-16-33-36)19(4)18(23)3/h5-6,13,15-17,20,31,34H,7-12,14H2,1-4H3,(H2,30,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM274105 (US10071079, Example 891 | US10478424, Example 891) Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CC1)C(=O)CCNCC(N)=O)-c1cn2ncnc2c(C)c1C Show InChI InChI=1S/C29H37N7O2/c1-17(2)27-22-13-21(20-8-11-35(12-9-20)26(38)7-10-31-14-25(30)37)5-6-24(22)34-28(27)23-15-36-29(32-16-33-36)19(4)18(23)3/h5-6,13,15-17,20,31,34H,7-12,14H2,1-4H3,(H2,30,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10478424 (2019) BindingDB Entry DOI: 10.7270/Q2QZ2DB0
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Homo sapiens (Human))	BDBM274105 (US10071079, Example 891 | US10478424, Example 891) Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CC1)C(=O)CCNCC(N)=O)-c1cn2ncnc2c(C)c1C Show InChI InChI=1S/C29H37N7O2/c1-17(2)27-22-13-21(20-8-11-35(12-9-20)26(38)7-10-31-14-25(30)37)5-6-24(22)34-28(27)23-15-36-29(32-16-33-36)19(4)18(23)3/h5-6,13,15-17,20,31,34H,7-12,14H2,1-4H3,(H2,30,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10478424 (2019) BindingDB Entry DOI: 10.7270/Q2QZ2DB0
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Homo sapiens (Human))	BDBM274105 (US10071079, Example 891 | US10478424, Example 891) Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CC1)C(=O)CCNCC(N)=O)-c1cn2ncnc2c(C)c1C Show InChI InChI=1S/C29H37N7O2/c1-17(2)27-22-13-21(20-8-11-35(12-9-20)26(38)7-10-31-14-25(30)37)5-6-24(22)34-28(27)23-15-36-29(32-16-33-36)19(4)18(23)3/h5-6,13,15-17,20,31,34H,7-12,14H2,1-4H3,(H2,30,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair
Toll-like receptor 9 (Homo sapiens (Human))	BDBM274105 (US10071079, Example 891 | US10478424, Example 891) Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CC1)C(=O)CCNCC(N)=O)-c1cn2ncnc2c(C)c1C Show InChI InChI=1S/C29H37N7O2/c1-17(2)27-22-13-21(20-8-11-35(12-9-20)26(38)7-10-31-14-25(30)37)5-6-24(22)34-28(27)23-15-36-29(32-16-33-36)19(4)18(23)3/h5-6,13,15-17,20,31,34H,7-12,14H2,1-4H3,(H2,30,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	534	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10478424 (2019) BindingDB Entry DOI: 10.7270/Q2QZ2DB0
					More data for this Ligand-Target Pair
Toll-like receptor 9 (Homo sapiens (Human))	BDBM274105 (US10071079, Example 891 | US10478424, Example 891) Show SMILES CC(C)c1c([nH]c2ccc(cc12)C1CCN(CC1)C(=O)CCNCC(N)=O)-c1cn2ncnc2c(C)c1C Show InChI InChI=1S/C29H37N7O2/c1-17(2)27-22-13-21(20-8-11-35(12-9-20)26(38)7-10-31-14-25(30)37)5-6-24(22)34-28(27)23-15-36-29(32-16-33-36)19(4)18(23)3/h5-6,13,15-17,20,31,34H,7-12,14H2,1-4H3,(H2,30,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	534	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company US Patent					Assay Description HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...				US Patent US10071079 (2018) BindingDB Entry DOI: 10.7270/Q2VD71GV
					More data for this Ligand-Target Pair