Compile Data Set for Download or QSAR

Found 6 hits of ic50 for monomerid = 276087   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 2B (Homo sapiens (Human))	BDBM276087 (1-(4-chlorophenyl)-4-{1H-[1,2,3]triazolo[4,5-c]pyr...) Show SMILES Clc1ccc(cc1)-n1cnc(c1)-c1cc2[nH]nnc2cn1 Show InChI InChI=1S/C14H9ClN6/c15-9-1-3-10(4-2-9)21-7-14(17-8-21)11-5-12-13(6-16-11)19-20-18-12/h1-8H,(H,18,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10071984 (2018) BindingDB Entry DOI: 10.7270/Q24Q7X0X
					More data for this Ligand-Target Pair
Lysine-specific demethylase 2A (Homo sapiens (Human))	BDBM276087 (1-(4-chlorophenyl)-4-{1H-[1,2,3]triazolo[4,5-c]pyr...) Show SMILES Clc1ccc(cc1)-n1cnc(c1)-c1cc2[nH]nnc2cn1 Show InChI InChI=1S/C14H9ClN6/c15-9-1-3-10(4-2-9)21-7-14(17-8-21)11-5-12-13(6-16-11)19-20-18-12/h1-8H,(H,18,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of FBXL11 was determined in 384-well plate format under the following reaction conditions: 0.15...				US Patent US10071984 (2018) BindingDB Entry DOI: 10.7270/Q24Q7X0X
					More data for this Ligand-Target Pair
Lysine-specific demethylase 2B (Homo sapiens (Human))	BDBM276087 (1-(4-chlorophenyl)-4-{1H-[1,2,3]triazolo[4,5-c]pyr...) Show SMILES Clc1ccc(cc1)-n1cnc(c1)-c1cc2[nH]nnc2cn1 Show InChI InChI=1S/C14H9ClN6/c15-9-1-3-10(4-2-9)21-7-14(17-8-21)11-5-12-13(6-16-11)19-20-18-12/h1-8H,(H,18,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 2A (Homo sapiens (Human))	BDBM276087 (1-(4-chlorophenyl)-4-{1H-[1,2,3]triazolo[4,5-c]pyr...) Show SMILES Clc1ccc(cc1)-n1cnc(c1)-c1cc2[nH]nnc2cn1 Show InChI InChI=1S/C14H9ClN6/c15-9-1-3-10(4-2-9)21-7-14(17-8-21)11-5-12-13(6-16-11)19-20-18-12/h1-8H,(H,18,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description PHF8 Assay: The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction condit...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Histone lysine demethylase PHF8 (Homo sapiens (Human))	BDBM276087 (1-(4-chlorophenyl)-4-{1H-[1,2,3]triazolo[4,5-c]pyr...) Show SMILES Clc1ccc(cc1)-n1cnc(c1)-c1cc2[nH]nnc2cn1 Show InChI InChI=1S/C14H9ClN6/c15-9-1-3-10(4-2-9)21-7-14(17-8-21)11-5-12-13(6-16-11)19-20-18-12/h1-8H,(H,18,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>500	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description PHF8 Assay: The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction condit...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Isoform 2 of Histone lysine demethylase PHF8 (2) (Homo sapiens (Human))	BDBM276087 (1-(4-chlorophenyl)-4-{1H-[1,2,3]triazolo[4,5-c]pyr...) Show SMILES Clc1ccc(cc1)-n1cnc(c1)-c1cc2[nH]nnc2cn1 Show InChI InChI=1S/C14H9ClN6/c15-9-1-3-10(4-2-9)21-7-14(17-8-21)11-5-12-13(6-16-11)19-20-18-12/h1-8H,(H,18,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...				US Patent US10071984 (2018) BindingDB Entry DOI: 10.7270/Q24Q7X0X
					More data for this Ligand-Target Pair