Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 288253   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent calcium channel gamma-8 subunit (Homo sapiens (Human))	BDBM288253 (5-(2-Isopropyl-6-(trifluoromethyl)pyrazolo[1,5-a]p...) Show SMILES CC(C)c1cc2ccc(c(-c3cc4CC(=O)Nc4c(C)c3)n2n1)C(F)(F)F Show InChI InChI=1S/C20H18F3N3O/c1-10(2)16-9-14-4-5-15(20(21,22)23)19(26(14)25-16)13-6-11(3)18-12(7-13)8-17(27)24-18/h4-7,9-10H,8H2,1-3H3,(H,24,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0160	n/a	n/a	n/a	n/a	7.4	n/a
Janssen Pharmaceutica NV US Patent					Assay Description This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...				US Patent US10087185 (2018) BindingDB Entry DOI: 10.7270/Q2QZ2D0H
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