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Compile Data Set for Download or QSAR

Found 2 hits of ic50 for monomerid = 293697   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lysine-specific demethylase 6B


(Homo sapiens (Human))
BDBM293697
PNG
(3-({[(4S)-7-(2-chlorophenyl)-3,4-dihydro-2H-1-benz...)
Show SMILES OC(=O)c1ccncc1NC[C@H]1CCOc2cc(ccc12)-c1ccccc1Cl |r|
Show InChI InChI=1S/C22H19ClN2O3/c23-19-4-2-1-3-16(19)14-5-6-17-15(8-10-28-21(17)11-14)12-25-20-13-24-9-7-18(20)22(26)27/h1-7,9,11,13,15,25H,8,10,12H2,(H,26,27)/t15-/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 550n/an/an/an/an/a25



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The enzymatic assay of JMJD3 activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test com...


US Patent US10106534 (2018)


BindingDB Entry DOI: 10.7270/Q2JW8GZX
More data for this
Ligand-Target Pair
Lysine-specific demethylase 4C


(Homo sapiens (Human))
BDBM293697
PNG
(3-({[(4S)-7-(2-chlorophenyl)-3,4-dihydro-2H-1-benz...)
Show SMILES OC(=O)c1ccncc1NC[C@H]1CCOc2cc(ccc12)-c1ccccc1Cl |r|
Show InChI InChI=1S/C22H19ClN2O3/c23-19-4-2-1-3-16(19)14-5-6-17-15(8-10-28-21(17)11-14)12-25-20-13-24-9-7-18(20)22(26)27/h1-7,9,11,13,15,25H,8,10,12H2,(H,26,27)/t15-/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.50E+3n/an/an/an/an/a25



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10106534 (2018)


BindingDB Entry DOI: 10.7270/Q2JW8GZX
More data for this
Ligand-Target Pair