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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 31135   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Arachidonate 5-lipoxygenase


(Homo sapiens (Human))
BDBM31135
PNG
(5-hydroxy-1H-benzo[g]indole-3-carboxylate, 11n)
Show SMILES CCOC(=O)c1c(CCc2ccc(Cl)cc2)[nH]c2c1cc(O)c1ccccc21
Show InChI InChI=1S/C23H20ClNO3/c1-2-28-23(27)21-18-13-20(26)16-5-3-4-6-17(16)22(18)25-19(21)12-9-14-7-10-15(24)11-8-14/h3-8,10-11,13,25-26H,2,9,12H2,1H3
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 49n/a 2.80E+3n/an/an/an/a



Friedrich Alexander University Erlangen



Assay Description
For determination of the activity of 5-LO in 40000g supernatant (S40), aliquots of the supernatants were added to reaction mix, and were preincubated...


J Med Chem 52: 3474-83 (2009)


Article DOI: 10.1021/jm900212y
BindingDB Entry DOI: 10.7270/Q2HM56S5
More data for this
Ligand-Target Pair