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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 314284   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Intermediate conductance calcium-activated potassium channel protein 4


(Homo sapiens (Human))
BDBM314284
PNG
(US9611232, Example 15)
Show SMILES NC(=O)CN1[C@@H](c2ccccc2F)C(OC1=O)(c1cccc(F)c1)c1cccc(F)c1 |r|
Show InChI InChI=1S/C23H17F3N2O3/c24-16-7-3-5-14(11-16)23(15-6-4-8-17(25)12-15)21(18-9-1-2-10-19(18)26)28(13-20(27)29)22(30)31-23/h1-12,21H,13H2,(H2,27,29)/t21-/m0/s1
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US Patent
n/an/a 42n/an/an/an/an/an/a



Hoffmann-La Roche Inc.

US Patent


Assay Description
Compounds were tested using a PatchXpress® (Model 7000A, Molecular Devices, Union City Calif.) on CHO cells over-expressing h KCa3.1 at ChanTest Corp...


US Patent US9611232 (2017)


BindingDB Entry DOI: 10.7270/Q2P84DZM
More data for this
Ligand-Target Pair